NovoSeven RT

Generic Name: Coagulation Factor VIIa (Recombinant)

  • What is NovoSeven RT?

    NovoSeven RT is a medication used to treat bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX and in patients with acquired hemophilia. It is used in the prevention of bleeding in surgical interventions or invasive procedures in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX and in patients with acquired hemophilia.

    NovoSeven RT is also used in the treatment of bleeding episodes in patients with congenital Factor VII deficiency and prevention of bleeding in surgical interventions or invasive procedures in patients with congenital Factor VII deficiency.

  • What is the most important information I should know about NovoSeven RT?

    After taking NovoSeven RT, some patients have more of a risk of thrombosis, which occurs when a clot forms in a blood vessel. Although the extent of this risk is not known, it is thought to be small. Some patients have conditions that may increase this risk. These conditions include clogged arteries, blood clots that form throughout the body instead of at the place of injury, a type of blood poisoning called septicemia, and crush injury, which is when a body part is crushed or squeezed between heavy or immobile objects.

    You should also be aware of early signs of having an allergy to this medication such as hives, itchy, swollen, red bumps or welts on the skin, tightness of the chest, wheezing, and low blood pressure.

  • Who should not take NovoSeven RT?

    You should use this medication with caution if you are pregnant or breastfeeding; the effects of this medicine on pregnant women are unknown.

    You should not take this medication if you are allergic to NovoSeven RT or any of its components.

  • What should I tell my doctor before I take the first dose of NovoSeven RT?

    Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with NovoSeven RT. Also, talk to your doctor about your complete medical history, especially if you have any allergies to this medication or any of its components.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Hemophilia A or B with Inhibitors for bleeding episodes

    Adults: The usual dosage is 90 micrograms per 2.2 pounds of body weight by injection every 2 hours until bleeding stops

    Hemophilia A or B with Inhibitors

    Adults: The usual dosage is 90 micrograms per 2.2 pounds of body weight immediately before surgery and every 2 hours during surgery

    Congenital FVII Deficiency

    Adults: The usual dosage is 15-30 micrograms per 2.2 pounds of body weight every 4-6 hours until bleeding stops

    Acquired Hemophilia

    Adults: The usual dosage is 70-90 micrograms per 2.2 pounds of body weight every 2-3 hours until bleeding stops

  • How should I take NovoSeven RT?

    NovoSeven RT is given intravenously (IV). It will be given to you as a bolus injection given over 2-5 minutes. The dosage and frequency will vary depending on your condition.
  • What should I avoid while taking NovoSeven RT?

    Avoid contact sports and activities that may lead to injury.
  • What are possible food and drug interactions associated with NovoSeven RT?

    If NovoSeven RT is taken with certain other drugs, the effect of either medication could be increased, decreased, or altered. It is especially important to check with your doctor before combining NovoSeven RT with any medications.

    You should especially avoid this medication if you are using other forms of NovoSeven. Medications such as coagulation factor concentrates and antifibrinolytic therapies should not be used with this medication.

  • What are the possible side effects of NovoSeven RT?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: bleeding, fever, injection site reaction, joint pain, headache, hypertension, hypotension, nausea/vomiting, pain, rash, swelling

  • Can I receive NovoSeven RT if I am pregnant or breastfeeding?

    You should use this medication with caution if you are pregnant or breastfeeding; the effects of this medicine on pregnant women are unknown.
  • What should I do if I miss a dose of NovoSeven RT?

    This medication will be administered by your healthcare professional. If bleeding is noticed after a missed dose, you will be given the missed dose. If no signs of bleeding are noticed, you may wait until your next scheduled dose.
  • How should I store NovoSeven RT?

    Your healthcare professional will follow the instructions in the package insert for appropriate storage conditions.