Generic Name: Tapentadol

  • What is Nucynta?

    Nucynta is a medicine used in adults to treat moderate to severe pain that is expected to last a short time. Nucynta is for short-term use only because the risks of withdrawal symptoms, abuse, and addiction are higher when Nucynta is used for longer periods of time.

  • What is the most important information I should know about Nucynta?

    Nucynta is a federally controlled substance because it can be abused. Tell your doctor if you (or a family member) have ever abused or been dependent on alcohol, prescription medicines, or street drugs. There is a risk of abuse or addiction with narcotic pain medicines. If you have abused drugs in the past, you may have a higher chance of developing abuse or addiction again while using Nucynta.

    Call your doctor right away or get emergency medical help if you have trouble breathing; a slow heartbeat; severe sleepiness; cold, clammy skin; feel faint, dizzy, confused, or cannot think, walk, or talk normally; have a seizure; or have hallucinations.

    Nucynta can cause physical dependence. Talk to your doctor about slowly stopping Nucynta to avoid getting sick with withdrawal symptoms. Tell your doctor if you have any of these symptoms of withdrawal: feeling anxious, sweating, sleep problems, shivering, pain, nausea, tremors, diarrhea, upper respiratory symptoms, hallucinations, and hair "standing on end." Physical dependence is not the same as drug addiction.

    Serotonin syndrome is a rare, life-threatening problem that could happen if you take Nucynta with certain antidepressant/psychiatric medications and migraine treatments known as triptans. Call your doctor or get medical help right away if you feel agitated, have hallucinations, a rapid heartbeat, loss of coordination, overactive reflexes, nausea, vomiting, diarrhea, or feel overheated.

    Nucynta can cause seizures in people who are at risk for or have seizures.

  • Who should not take Nucynta?

    Do not take Nucynta if you have severe lung problems, have a condition called paralytic ileus (impairment of small intestines), or have taken a monoamine oxidase inhibitor (MAOI), an antidepressant/psychiatric medication, within the last 14 days. Ask your doctor or pharmacist if any of your medicines is an MAOI.

    Do not use Nucynta if it has not been prescribed for you. You should not take Nucynta if your pain is mild and can be controlled with other pain medicines such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen (Tylenol).

  • What should I tell my doctor before I take the first dose of Nucynta?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Nucynta. Also, talk to your doctor about your complete medical history, especially if you have trouble breathing or lung problems, a history of head injury, liver or kidney problems, convulsions or seizures, dependency problems with alcohol, pancreas or gallbladder problems, past or present substance abuse or drug addiction, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you depending on the level of your pain.

  • How should I take Nucynta?

    Take Nucynta exactly as prescribed by your doctor. Do not change the dose of Nucynta or take more than prescribed. Call your doctor if your pain is not well controlled while taking Nucynta. Your doctor may change your dose after seeing how the medicine affects you.

  • What should I avoid while taking Nucynta?

    Nucynta can cause sleepiness. Avoid driving, operating machinery, or participating in any other possibly dangerous activities until you know how you react to this medicine.

    Avoid drinking alcohol while taking Nucynta. Alcohol increases your chance of having dangerous side effects.

    Avoid starting any new medicines while taking Nucynta without checking first with your doctor. Certain medicines or classes of medicines may harmfully interact with Nucynta.

    Do not give Nucynta to other people, even if they have the same symptoms you have. Sharing Nucynta could be harmful and is against the law.

  • What are possible food and drug interactions associated with Nucynta?

    If Nucynta is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nucynta with the following: alcohol; any medicine that makes you sleepy; certain antidepressant/psychiatric medications in classes known as MAOIs, serotonin and norepinephrine reuptake inhibitors (SNRIs), and selective serotonin reuptake inhibitors (SSRIs); or triptans (migraine medications).

  • What are the possible side effects of Nucynta?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: low blood pressure, nausea, dizziness, vomiting, sleepiness, itching, constipation

  • Can I receive Nucynta if I am pregnant or breastfeeding?

    The effects of Nucynta during pregnancy and breastfeeding are unknown. Nucynta should only be used during pregnancy if the potential benefit justifies the risk to the unborn baby. Do not breastfeed while taking Nucynta. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Nucynta?

    Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Nucynta?

    Store at room temperature. Keep tablets dry and protect from moisture. Dispose of tablets you no longer need.

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