What is Oleptro?Oleptro is used to treat depression in adults.
What is the most important information I should know about Oleptro?Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. People who have, or have a family history of, bipolar illness (also called manic depressive illness) or who already have suicidal thoughts or actions may be at a higher risk.
Sudden changes in mood, behaviors, thoughts, or feelings should be closely monitored for and reported when an antidepressant medicine is started or when the dose is changed. Call your doctor right away if you experience any suicidal thoughts or attempts, new or worsening depression, anxiety, agitation, panic attacks, or aggressive and dangerous behavior. It is important to keep all follow-up visits with your doctor.
Do not stop taking Oleptro without first talking to your doctor; stopping suddenly can cause other symptoms.
Serotonin syndrome or neuroleptic malignant syndrome is a life-threatening problem that could occur if you take Oleptro with certain other antidepressant/psychiatric drugs or with migraine drugs known as triptans. Call your doctor and get immediate medical help if you feel agitated, have hallucinations, problems with coordination, fast or irregular heartbeat, tight muscles, trouble walking, nausea, vomiting, or diarrhea. Other signs of serotonin syndrome may include feeling high, then becoming irritable; being unable to sleep or stop talking (mania); low blood pressure; unusual bleeding or bruising; erection lasting for more than 6 hours; and symptoms of low sodium levels (such as headaches, weakness, feeling confused, or trouble with concentration and memory).
Who should not take Oleptro?Do not take Oleptro if you have been taking an antidepressant/psychiatric medicine known as a monoamine oxidase inhibitor (MAOI) within 14 days of starting treatment.
What should I tell my doctor before I take the first dose of Oleptro?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Oleptro. Also, talk to your doctor about your complete medical history, especially if you have heart problems, including QT prolongation (or a family history of it), have ever had a heart attack, bipolar disorder, liver or kidney problems, other serious medical conditions, are pregnant, plan to become pregnant, are breastfeeding, or have taken an MAOI or have stopped taking an MAOI in the last 2 weeks.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The starting dose of Oleptro is 150 milligrams (mg) once a day. Your doctor may increase the dose by 75 mg per day every 3 days. The maximum daily dose is 375 mg.
How should I take Oleptro?Take Oleptro exactly as prescribed by your doctor. Do not stop taking Oleptro without talking to your doctor.
Take Oleptro at the same time every day, in the late evening (preferably at bedtime), on an empty stomach.
Oleptro should be swallowed whole or broken in half along the score line. Do not chew or crush Oleptro. Tell your doctor if you cannot swallow Oleptro either whole or as a half tablet.
What should I avoid while taking Oleptro?Do not drive, operate heavy machinery, or do other dangerous activities until you know how Oleptro affects you. Oleptro can slow your thinking and motor skills.
Do not drink alcohol or take other medicines that make you sleepy or dizzy while taking Oleptro until you talk with your doctor, as Oleptro may worsen these symptoms.
What are possible food and drug interactions associated with Oleptro?If Oleptro is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Oleptro with the following: alcohol, antipsychotics, aspirin, other CNS depressants, carbamazepine, digoxin, ketoconazole, indinavir, itraconazole, MAOIs, nonsteroidal anti-inflammatory drugs or other drugs that affect bleeding, phenytoin, antidepressant/psychiatric medicines in classes known as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), triptans (migraine medicines), tryptophan, or warfarin.
What are the possible side effects of Oleptro?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: sleepiness, dizziness, constipation, blurry vision
Can I receive Oleptro if I am pregnant or breastfeeding?Oleptro may harm an unborn baby. Talk to your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Oleptro?Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Oleptro?Store at room temperature.
- Alcohol and AntidepressantsThe dos and don'ts of drinking when you take antidepressants are mostly don'ts.
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- Medications to Avoid While on AntidepressantsCould your antidepressant interact with something else you're taking?