Oleptro

Generic Name: Trazodone

  • What is this medication and its most common uses?

    Oleptro is a medicine used to treat depression. Oleptro is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day).

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Oleptro is thought to work by increasing the activity of a chemical in your brain called serotonin. By increasing serotonin, Oleptro may help improve your symptoms.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Oleptro has been shown to improve symptoms of depression.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Oleptro exactly as your healthcare provider has prescribed.

    How do I know it is working?

    Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Oleptro can increase the risk of suicidal thoughts and behavior in children, teenagers, and young adults. Your healthcare provider will monitor you closely for clinical worsening and suicidal/unusual behavior after you start taking Oleptro or start a new dose of Oleptro. Tell your healthcare provider right away if you have thoughts about suicide or dying; attempts to commit suicide; new or worse depression, anxiety, or irritability; feel agitated or restless; have panic attacks or trouble sleeping; act on dangerous impulses; have an extreme increase in activity and talking; or other unusual changes in your behavior or mood.

    More common side effects may include: drowsiness, dizziness, constipation, blurry vision.

    Less common side effects may include:

    Serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) with symptoms such as mental status changes (such as agitation or hallucinations), a fast heartbeat, sweating or fever, coordination problems or muscle twitching, muscle stiffness, nausea, vomiting, or diarrhea.

    Manic episodes with symptoms such as greatly increased energy, severe trouble sleeping, racing thoughts, reckless behavior, excessive happiness or irritability, or talking faster than usual.

    Changes in the electrical activity of your heart, with symptoms such as chest pain, fast or slow heartbeat, shortness of breath, and dizziness or fainting.

    Abnormal bleeding or bruising, especially if you also take blood thinners (such as warfarin), nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen or naproxen), or aspirin.

    Low blood sodium (salt) levels with symptoms such as headache, weakness, unsteady feeling, confusion, problems concentrating or thinking, or memory problems.

    Low blood pressure, with symptoms such as feeling dizzy or fainting when you change positions from sitting to standing.

    Oleptro may also cause a painful, prolonged erection, lasting for more than 6 hours.

  • Who should not take this medication?

    Do not take Oleptro if you are allergic to it or any of its ingredients.

    Do not take Oleptro if you take another medicine called a monoamine oxidase inhibitor (MAOI) (such as phenelzine, selegiline, or linezolid), a class of medications used to treat depression and other conditions. Do not start taking Oleptro if you stopped taking an MAOI in the last 2 weeks.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Oleptro. Also, talk to your healthcare provider about your complete medical history, especially if you have liver or kidney problems; bipolar disorder; heart problems (including a heart attack, or QT prolongation [very fast or abnormal heartbeats] or a family history of it); or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: The recommended starting dose is 150 milligrams once a day. Your healthcare provider may adjust your dose appropriately.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Oleptro exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Oleptro without first talking to your healthcare provider.

    Take Oleptro at the same time every day, in the late evening (preferably at bedtime), on an empty stomach.

    Oleptro tablets should be swallowed whole or taken as a half tablet by breaking the tablet along the score line, as directed by your healthcare provider.

    Do not chew or crush Oleptro.

  • What should I avoid while taking this medication?

    Do not drive, operate heavy machinery, or engage in other dangerous activities until you know how Oleptro affects you.

    Do not drink alcohol or take other medicines that make you sleepy or dizzy while you are taking Oleptro.

  • What are the possible food and drug interactions associated with this medication?

    If Oleptro is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Oleptro may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Oleptro during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Oleptro, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

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