Opana ER

Generic Name: Oxymorphone

  • What is this medication and its most common uses?

    Opana ER is a medicine used to treat moderate to severe around-the-clock pain. Opana ER is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day).

    Opana ER is a federally controlled substance because it has abuse potential.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Opana ER works in your central nervous system (the brain and spinal cord) and affects the way your body responds to pain.

    Opana ER is not used to treat pain that you only have now and then ("as needed"), or after surgery if the pain is mild or not expected to last for a long period.

    What are the beneficial effects of this medication and when should I begin to have results?

    What: Opana ER has been shown to help relieve pain.

    When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Opana ER exactly as your healthcare provider has prescribed.

    How do I know it is working?

    You may feel an improvement in your pain. That is a good indicator that the medicine is working. Your healthcare provider may also ask you questions from time to time to assess how well your symptoms are controlled with treatment.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    Opana ER has abuse potential. This chance is higher if you are or have ever been addicted to or abused other medicines, street drugs, or alcohol, or if you have a history of mental health problems. If you have concerns, talk to your healthcare provider for more information about abuse and addiction. Do not share Opana ER with others and take steps to protect Opana ER from theft or misuse.

    Serious, life-threatening breathing problems may occur when taking Opana ER, even when Opana ER has been taken as recommended and not misused or abused. Tell your healthcare provider right away if you are breathing more slowly than usual; are experiencing shallow breathing (little chest movement while breathing); or if you feel faint, dizzy, confused, or have any other unusual symptoms.

    Keep Opana ER in a safe place. Accidental use, especially in children, may result in serious harm and may be life-threatening.

    Alcohol can increase the levels of Opana ER in the body and cause a potential life-threatening overdose of Opana ER. Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol while taking Opana ER.

    More common side effects may include: nausea, constipation, dizziness, drowsiness, vomiting, hives, headache, increased sweating, dry mouth, diarrhea, trouble sleeping, fatigue, decreased appetite, abdominal (stomach area) pain.

    Less common side effects may include:

    Sudden fall in your blood pressure with symptoms such as dizziness, lightheadedness, or fainting when rising too quickly from a sitting or lying position.

  • Who should not take this medication?

    Do not take Opana ER if you are allergic to it, any of its ingredients, or to similar medicines (such as codeine).

    Do not take Opana ER if you are having an asthma attack, or if you have severe asthma, trouble breathing, or other lung problems.

    Do not take Opana ER if you have a bowel blockage or narrowing of your stomach or intestines.

    Do not take Opana ER if you have liver problems.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Opana ER. Also, talk to your healthcare provider about your complete medical history, especially if you have trouble breathing or lung problems; a head injury or brain problems; liver, kidney, thyroid, adrenal glands, or pancreas problems; seizures; problems urinating or enlargement of your prostate; mental health problems; or a history of drug or alcohol addiction or a family history of these problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Adults: Your healthcare provider will prescribe the appropriate dose for you based on your previous pain medication and the type and severity of your pain.

    If you are elderly or have kidney or liver impairment, your healthcare provider may adjust your dose appropriately.

    It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

  • How should I take this medication?

    Take Opana ER exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Opana ER without first talking to your healthcare provider.

    Take Opana ER at the same time every day, on an empty stomach, at least 1 hour before or 2 hours after meals.

    Swallow Opana ER tablets whole. Do not cut, break, chew, crush, dissolve, or inject Opana ER. If you do not take Opana ER whole, the medicine will be released into your body too fast, causing you to have trouble breathing and life-threatening effects.

    When you stop taking Opana ER, flush the remaining tablets down the toilet.

  • What should I avoid while taking this medication?

    Do not drink alcohol or take prescription or over-the-counter medicines that contain alcohol while you are taking Opana ER.

    Do not drive a car, operate machinery, or engage in other dangerous activities until you know how Opana ER affects you.

  • What are the possible food and drug interactions associated with this medication?

    If Opana ER is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Opana ER with the following: alcohol, anticholinergic agents (such as ipratropium or oxybutynin), certain pain medicines (such as buprenorphine, butorphanol, nalbuphine, or pentazocine), cimetidine, or other medicines that may make you sleepy (such as alprazolam, morphine, or chlorpromazine).

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Opana ER during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Opana ER, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

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I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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