Generic Name: Pimozide

  • What is Orap?

    Orap is a medicine used to treat the symptoms of Tourette's Disorder, such as twitching and spasms known as tics, in people who have failed to respond to standard treatment.

  • What is the most important information I should know about Orap?

    Do not use Orap to treat simple tics or tics other than those associated with Tourette's Disorder.

    The use of Orap has possible risks, such as tardive dyskinesia (abnormal muscle movements, including tremor, shuffling, and uncontrolled, involuntary movements) and neuroleptic malignant syndrome (NMS) (a life-threatening brain disorder).

    If you have a history of significantly low white blood cell counts and take Orap, you may get certain conditions that can be very dangerous.

  • Who should not take Orap?

    Do not use Orap if you are taking other medications that can cause motor tics, such as stimulants (amphetamines). You can take Orap if you stop taking those medications so that your doctor can determine whether your tics are caused by medications or Tourette's Disorder.

    Do not use Orap if you have a history of heart disease from birth, cardiac arrhythmias (life-threatening irregular heartbeats), or if you are taking medications that can affect your heart.

    Do not take Orap if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Orap?

    Tell your doctor about all prescriptions, over-the-counter, and herbal medications you are taking before beginning treatment with Orap. Also, talk to your doctor about your complete medical history, especially if you have a history of low white blood cell counts, cardiac arrhythmias, or liver or kidney problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended starting dose is 1-2 milligrams (mg) a day, divided into smaller doses. Your doctor may increase your dose as appropriate.

    Children: Your doctor will prescribe the appropriate dose for your child, based on their weight.

  • How should I take Orap?

    Take Orap exactly as prescribed by your doctor.

  • What should I avoid while taking Orap?

    Do not drink grapefruit juice while you are taking Orap.

    Do not drive a car or operate machinery while you are taking Orap. Orap may impair your mental and physical abilities.

  • What are possible food and drug interactions associated with Orap?

    If Orap is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Orap may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.

  • What are the possible side effects of Orap?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: behavior changes, constipation, drowsiness, dry mouth, fever, heart or heartbeat problems, impaired or involuntary movements, impotence, muscle rigidity or tightness, visual disturbances

  • Can I receive Orap if I am pregnant or breastfeeding?

    The effects of Orap during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Orap?

    If you miss a dose of Orap, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Orap?

    Store at room temperature.