Orapred

Generic Name: Prednisolone

  • What is Orapred?

    Orapred is used for a variety of conditions as determined by your doctor, including severe allergies that cannot be otherwise treated, asthma (or asthma caused by different medical conditions), skin diseases, kidney problems in people with lupus (such as proteinuria), stomach problems (such as ulcerative colitis and Crohn's disease), leukemia and lymphomas, multiple sclerosis, eye problems, rheumatologic issues (such as rheumatoid arthritis), and tuberculous meningitis. It is available as an oral solution and as an orally disintegrating tablet (ODT).

  • What is the most important information I should know about Orapred?

    Do not stop your course of Orapred treatment abruptly.

    Call your doctor if you develop a fever while taking Orapred.

    Avoid exposure to chickenpox and measles. If you are exposed to chickenpox or measles, seek medical advice without delay.

    While being treated with Orapred, do not receive live vaccines, as this drug may suppress your immune system. You may receive killed or inactivated vaccines, but the body's response cannot be predicted.

  • Who should not take Orapred?

    Do not take Orapred if you have a fungal infection or if you are allergic to the drug or any of its components.

  • What should I tell my doctor before I take the first dose of Orapred?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking to avoid an interaction with Orapred. Also, talk to your doctor about your complete medical history, especially if you have a history of high blood pressure, heart problems (including congestive heart failure), kidney problems, stomach ulcers, a stomach infection, eye problems, myasthenia gravis, if you are going through menopause, if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The initial dose of Orapred may vary from 5 to 60 milligrams (mg) per day, depending on the specific condition being treated.

    Children: The initial dose of Orapred may vary depending on the specific condition being treated. The range of initial doses is 0.14 to 2 mg per 2.2 pounds of body weight per day in three or four divided doses.

    Asthma Uncontrolled by an Inhaler

    Children: The usual dosage is 1-2 mg per 2.2 pounds of body weight per day in single or divided doses.

    Kidney Problems

    Children: The usual dosage is 60 mg/m2/day given in three divided doses for 4 weeks, followed by 4 weeks of single dose alternate-day therapy at 40 mg/m2/day.

    Multiple Sclerosis

    Adults: The usual daily doses are 200 mg of Orapred for a week, followed by 80 mg every other day for one month.

  • How should I take Orapred?

    Do not remove Orapred ODT from its blister package until you are ready to use it. The blister pack should be peeled open, and the oral disintegrating tablet placed on your tongue, where tablets may be swallowed whole, or allowed to dissolve in the mouth, with or without water.

    Measure the liquid form of Orapred with a special dose-measuring spoon or cup, not a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist for one.

  • What should I avoid while taking Orapred?

    Take Orapred with food to avoid stomach upset.

    Do not go for skin tests while on Orapred.

    Do not break or use partial Orapred ODT tablets. Do not remove the tablet from the blister pack until right before you plan to use it.

  • What are possible food and drug interactions associated with Orapred?

    If Orapred is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Orapred with any of the following: aminoglutethimide, amphotericin-B, anticholinesterase agents, antidiabetic drugs, barbiturates, blood thinners, carbamazepine, cholestyramine, cyclosporine, digitalis glycosides, diuretics, ephedrine, estrogens (including oral contraceptives), isoniazid, ketoconazole, live or live attenuated vaccines, macrolide antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs, including aspirin and salicylates), phenytoin, rifampin, warfarin.

  • What are the possible side effects of Orapred?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: fluid retention, changes in glucose tolerance, increase in blood pressure, behavioral and mood changes, increased appetite, weight gain

  • What should I do if I miss a dose of Orapred?

    If you miss a dose of Orapred, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you are unsure, ask your doctor or pharmacist for advice.

  • How should I store Orapred?

    Store Orapred oral solution in the refrigerator. Keep tightly closed. Store Orapred ODT at room temperature away from light and moisture.

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