Generic Name: Levodopa

  • What is Parcopa?

    Parcopa is a medicine used to treat the symptoms of Parkinson's disease. Parcopa contains two medicines, carbidopa and levodopa.

  • What is the most important information I should know about Parcopa?

    The period of effectiveness after each dose may begin to shorten and you may notice more pronounced symptoms; this is called a "wearing-off" effect. Tell your doctor if this "wearing-off" effect is troublesome.

    Parcopa can cause mental disturbances. Contact your doctor immediately if you become depressed or experience any thoughts of suicide.

    Occasionally, dark color (red, brown, or black) can appear in your saliva, urine, or sweat after taking Parcopa. Although the color is not a cause for concern, it may stain your clothing.

    Parcopa can cause involuntary movements. Tell your doctor if you notice any of these, as a lower dose may be required.

    Do not change your dose or abruptly discontinue your treatment without first talking to your doctor. A condition that resembles neuroleptic malignant syndrome (a life-threatening brain disorder) can occur if you abruptly stop taking this medication.

  • Who should not take Parcopa?

    Do not take Parcopa if you are allergic to it or any of its ingredients, or if you are taking a nonselective monoamine oxidase inhibitor (MAOI), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine).

    Do not take Parcopa if you have narrow-angle glaucoma (eye damage disorder), or if you have undiagnosed skin lesions or a history of melanoma (skin cancer).

  • What should I tell my doctor before I take the first dose of Parcopa?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Parcopa. Also, talk to your doctor about your complete medical history, especially if you have severe heart problems, a history of heart attacks, irregular heartbeat, phenylketonuria (an inability to process phenylalanine, a protein in your body), psychosis, skin cancer, stomach ulcers, asthma, lung disorders, kidney or liver impairment, endocrine (hormonal) diseases, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will prescribe the appropriate dose for you, depending on the severity of your condition and other medications you have previously taken.

  • How should I take Parcopa?

    Take Parcopa exactly as prescribed by your doctor. Prior to taking this medicine, gently remove the tablet from the bottle with dry hands. Immediately place the tablet on the top of your tongue where it will dissolve in seconds; then swallow it with saliva. You do not need to take the tablet with liquids.

  • What should I avoid while taking Parcopa?

    Do not change your diet to foods that are high in protein because this may reduce the absorption of Parcopa.

  • What are possible food and drug interactions associated with Parcopa?

    If Parcopa is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Parcopa with the following: certain antidepressants (such as amitriptyline), dopamine blockers (such as chlorpromazine or haloperidol), iron supplements, isoniazid, MAOIs, metoclopramide, multivitamins with iron, papaverine, phenytoin, or risperidone.

  • What are the possible side effects of Parcopa?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, agitation, allergic reactions, back pain, bleeding, blurred vision, chest pain, confusion, constipation, cough, dark saliva, dark sweat, diarrhea, dizziness, dream abnormalities, drowsiness, dry mouth, fatigue, flushing skin, hallucinations (seeing things when they aren't really there), headache, heart attack, high or low blood pressure, hot flashes, irregular heartbeat, leg pain, muscle cramps, rash, shoulder pain, sweating, taste alterations, urinary tract infections, vomiting, weakness, weight gain or loss

  • Can I receive Parcopa if I am pregnant or breastfeeding?

    The effects of Parcopa during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Parcopa?

    If you miss a dose of Parcopa, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Parcopa?

    Store at room temperature.