Generic Name: Acetaminophen

  • What is Percocet?

    Percocet is a pain medicine that contains the narcotic painkiller oxycodone and the non-narcotic painkiller acetaminophen. Percocet is used to relieve moderate to moderately severe pain.

  • What is the most important information I should know about Percocet?

    Percocet has abuse potential. Mental and physical dependence can occur with the use of Percocet when it is used improperly.

    Percocet can cause serious breathing problems that can become life-threatening, especially when it is used in the wrong way. Tell your doctor if you have any lung or breathing problems; your doctor will monitor you.

    Percocet contains acetaminophen, which can cause severe liver injury. Do not take more than 4,000 milligrams (mg) of acetaminophen per day or take other products containing acetaminophen. The risk of liver injury can be higher if you have underlying liver disease or drink alcohol while you are taking Percocet.

    Percocet can cause allergic reactions or anaphylaxis (a serious and rapid allergic reaction that may result in death if not immediately treated). Stop taking Percocet and tell your doctor immediately if you develop a rash, difficulty breathing, or swelling of your face, mouth, or throat.

    Percocet can impair your mental or physical abilities. Do not drive or operate machinery until you know how Percocet affects you.

    Keep Percocet in a secure place out of the reach of children. In the case of accidental ingestion, get emergency medical care immediately.

  • Who should not take Percocet?

    Do not take Percocet if you are allergic to it, any of its ingredients, or other narcotic painkillers.

    Do not take Percocet if you have paralytic ileus (impairment of the small intestines), severe lung problems, or severe asthma.

  • What should I tell my doctor before I take the first dose of Percocet?

    Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Percocet. Also, talk to your doctor about your complete medical history, especially if you have ever had kidney or liver disease, hypothyroidism (an underactive thyroid gland), adrenal gland problems, heart disease, seizures, gallbladder problems, severe diarrhea, paralytic ileus, difficulty urinating, an enlarged prostate, stomach problems (such as an ulcer), a history of substance abuse or dependence, mental disorders (such as depression) or suicidal thoughts, low blood pressure, if you are taking medications to lower your blood pressure, or if you have experienced a head injury.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Percocet 2.5 mg/325 mg Tablets

    Adults: The usual dose is 1-2 tablets every 6 hours.

    All Other Percocet Strengths

    Adults: The usual dose is 1 tablet every 6 hours as needed for pain.

  • How should I take Percocet?

    Take Percocet exactly as prescribed by your doctor. Do not adjust your dose or discontinue Percocet without speaking to your doctor. Attempts to taper (gradually reduce the dose) or discontinue the medication should be made at specific intervals, through the guidance of your doctor.

  • What should I avoid while taking Percocet?

    Do not take Percocet with alcohol, other narcotic painkillers, tranquilizers (such as alprazolam or lorazepam), sedatives (such as diphenhydramine or phenobarbital), or other central nervous system (CNS) depressants unless under the recommendation and guidance of your doctor.

    Percocet can impair your mental and physical ability to perform potentially hazardous tasks (such as driving or operating heavy machinery). Do not participate in any activities that require full alertness until you know how Percocet effects you.

    Do not share Percocet with others; it may be habit-forming. Therefore, it should be used only by the person it was prescribed for.

    Dispose all unused tablets by flushing them down the toilet.

  • What are possible food and drug interactions associated with Percocet?

    If Percocet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Percocet with the following: alcohol; birth control pills; certain painkillers; diuretics (water pills) (such as furosemide); CNS depressants (such as alprazolam, diazepam, or phenobarbital); lamotrigine; probenecid; propranolol; sedative-hypnotics; or zidovudine.

  • What are the possible side effects of Percocet?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, difficulty breathing, dizziness, exaggerated feelings of well-being, high blood pressure, itching, lightheadedness, low blood pressure, nausea, sedation, skin rash, upset stomach, urinary retention (inability to urinate normally), vomiting

  • Can I receive Percocet if I am pregnant or breastfeeding?

    The effects of Percocet during pregnancy are unknown. Percocet can be found in your breast milk if you take it during breastfeeding. Do not take Percocet while you are breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Percocet?

    Percocet should be taken only as needed.

  • How should I store Percocet?

    Store at room temperature. Protect from heat, moisture, and light.