Generic Name: Doxycycline

  • What is Periostat?

    Periostat is an antibiotic used to treat periodontitis, a disease of the tissue that supports and attaches the teeth.

  • What is the most important information I should know about Periostat?

    Periostat may cause developing teeth to become permanently discolored. Children <8 years old, women in the last half of pregnancy, and breastfeeding mothers should not take this medication.

    As with other antibiotics, treatment with Periostat may result in a growth of bacteria that do not respond to this medication and can cause a secondary infection such as a fungal infection.

    You may become more sensitive to light while taking Periostat and may develop an exaggerated sunburn reaction. Be careful if you are going out in the sun or using a sunlamp. If you develop a skin rash, notify your doctor immediately.

  • Who should not take Periostat?

    Do not use Periostat if you are allergic to it or any other tetracycline antibiotic, such as minocycline.

    Children <8 years old, women in the last half of pregnancy, and breastfeeding mothers should not take this medication.

  • What should I tell my doctor before I take the first dose of Periostat?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Periostat. Also, talk to your doctor about your complete medical history, especially if you have lupus (a disease that affects the immune system), liver or kidney disease, if you are pregnant, plan to become pregnant, or are breastfeeding. In addition, tell your doctor if you have a history of fungal infections in your mouth and if you are taking birth control pills.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual dose is 20 milligrams (mg) twice a day at 12-hour intervals (in the morning and evening).

  • How should I take Periostat?

    Take Periostat with a full glass of water or other liquids to avoid irritating your throat or stomach. Take it at least one hour before or two hours after meals. Take Periostat for the entire length of time prescribed by your doctor.

  • What should I avoid while taking Periostat?

    Do not take antacids containing aluminum, calcium, or magnesium and iron-containing supplements before or after taking Periostat.

  • What are possible food and drug interactions associated with Periostat?

    If Periostat is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Periostat with the following: antacids containing aluminum, calcium, or magnesium; iron-containing preparations; barbiturates (such as phenobarbital); bismuth subsalicylate; blood-thinning medications (such as warfarin); carbamazepine; birth control pills; penicillin; methoxyflurane; and phenytoin.

  • What are the possible side effects of Periostat?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: common cold, diarrhea, flu symptoms, headache, joint pain, nausea, upset stomach

  • Can I receive Periostat if I am pregnant or breastfeeding?

    Periostat should not be used during pregnancy or breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Periostat?

    If you miss a dose of Periostat, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Periostat?

    Store at room temperature.