What is Persantine?Persantine helps reduce the formation of blood clots in people who have had heart valve surgery. It is used in combination with blood thinners such as warfarin. It may also be used for other conditions as determined by your doctor.
What is the most important information I should know about Persantine?If you need a medication for pain or fever, do not take aspirin without first consulting your doctor. Persantine is commonly given with the blood thinner warfarin. Aspirin should not be given together with blood thinners such as warfarin because the risk of bleeding may be increased.
Persantine has been known to cause liver problems, including liver failure.
Persantine may cause low blood pressure. Inform your doctor if you have low blood pressure prior to starting Persantine.
Persantine should be used with caution in patients who have severe heart problems because symptoms such as chest pain may worsen while taking this medication.
Who should not take Persantine?Do not take Persantine if you are allergic to the medication or to any of its ingredients.
What should I tell my doctor before I take the first dose of Persantine?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Persantine. Also, talk to your doctor about your complete medical history, especially if you have heart problems such as chest pain, recent heart attack, or coronary artery disease; liver problems; or low blood pressure.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The usual recommended dose is 75-100 milligrams (mg) 4 times a day. Persantine is usually taken in addition to a blood thinner such as warfarin.
Children ≥12 years: The usual recommended dose is 75-100 mg 4 times a day, usually in addition to a blood thinner such as warfarin.
How should I take Persantine?Persantine must be taken exactly as your doctor prescribes it.
What should I avoid while taking Persantine?Avoid aspirin if taking Persantine along with blood thinners such as warfarin.
What are possible food and drug interactions associated with Persantine?If Persantine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Persantine with the following: adenosine; Alzheimer's disease drugs such as donepezil, tacrine, and rivastigmine; anticholinesterases such as neostigmine; aspirin; and blood thinners such as warfarin.
What are the possible side effects of Persantine?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal distress, chest pain, dizziness, diarrhea, flushing, headache, itching, rash, vomiting
Can I receive Persantine if I am pregnant or breastfeeding?The effects of Persantine during pregnancy are unknown. Persantine is found in breast milk, and caution should be exercised when breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Persantine?If you miss a dose of Persantine, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at the same time.
How should I store Persantine?Store at room temperature.
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