Phenadoz

Generic Name: Promethazine

  • What is Phenadoz?

    Phenadoz is an antihistamine used to treat the symptoms of seasonal and year-round allergies, non-allergic runny nose, conjunctivitis ("pink eye") due to inhalant allergens and foods, or allergic skin reactions. In addition, Phenadoz is used to prevent or control pain or nausea and vomiting during and after surgery, and it is used for the treatment and prevention of motion sickness. It is also used to help produce light sleep. Phenadoz is available as a suppository.

  • What is the most important information I should know about Phenadoz?

    Phenadoz can cause drowsiness and impair mental or physical abilities. Do not drive or operate machinery until you know how Phenadoz affects you. Do not drink alcohol or take certain medicines that can cause drowsiness (such as sedatives and tranquilizers) without speaking to your doctor.

    Phenadoz should not be used in children less than two years of age. Serious and sometimes fatal breathing problems can occur when Phenadoz is used by children in this age group.

    Neuroleptic malignant syndrome (NMS) (a life-threatening brain disorder) can occur if you take Phenadoz. Tell your doctor immediately if you develop a fever, stiff muscles, fast or irregular heartbeat, or sweating.

    Phenadoz should be used with caution if you have a seizure disorder, are taking other medications that can increase your risk for seizures, have a breathing problem or lung disease, or have bone marrow depression.

  • Who should not take Phenadoz?

    Do not take Phenadoz if you are allergic to it or any of its ingredients. Also, do not take Phenadoz for the treatment of lower respiratory (lung) tract symptoms, including asthma. Children less than two years of age should not take Phenadoz.

  • What should I tell my doctor before I take the first dose of Phenadoz?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Phenadoz. Also, talk to your doctor about your complete medical history, especially if you have central nervous system (CNS) problems, bone marrow depression, asthma or lung disease, glaucoma (high pressure in the eye), stomach or intestinal disorders, urinary problems caused by enlargement of your prostate gland or blockage of your bladder, heart problems, liver problems, Reye's syndrome (a potentially fatal disease of the brain and liver that most commonly occurs in children after a viral infection, such as chickenpox), alcoholism, are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥2 years: Your doctor will prescribe the appropriate dose for you based on your age and condition.

  • How should I take Phenadoz?

    Take Phenadoz exactly as prescribed by your doctor.

    Phenadoz suppositories are for rectal use only.

  • What should I avoid while taking Phenadoz?

    Do not drive or operate machinery until you know how Phenadoz affects you.

    Do not drink alcohol or take certain medicines that can cause drowsiness without consulting your doctor.

    Do not expose yourself to the sun for a long time. Phenadoz can make you become more sensitive to sunlight.

  • What are possible food and drug interactions associated with Phenadoz?

    If Phenadoz is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Phenadoz with the following: alcohol, anticholinergics (such as atropine or ipratropium), certain medicines that can cause drowsiness (such as alprazolam, diazepam, or oxycodone), epinephrine, or monoamine oxidase inhibitors (MAOIs), a class of drugs used to treat depression and other psychiatric conditions (such as phenelzine).

  • What are the possible side effects of Phenadoz?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, blurred vision, breathing difficulty, changes in your blood pressure or heartbeat, confusion, disorientation, dizziness, drowsiness, dry mouth, faintness, hallucinations, involuntary muscle movements, nausea, NMS, overly excited, rash, seizures, sensitivity to light, sleepiness, vomiting, yellowing of your skin or whites of your eyes

    If you experience symptoms of NMS, contact your doctor immediately.

  • Can I receive Phenadoz if I am pregnant or breastfeeding?

    The effects of Phenadoz during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Phenadoz?

    If you miss a dose of Phenadoz, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    For certain conditions, Phenadoz should be given under special circumstances determined by your doctor or given only as needed.

  • How should I store Phenadoz?

    Store in the refrigerator.