What is Phoslyra?Phoslyra is a medicine used to reduce blood phosphorus levels in people with end-stage renal disease (when the kidneys stop working well enough for you to live without dialysis or a transplant).
What is the most important information I should know about Phoslyra?Phoslyra can cause an increase in your blood calcium levels. Do not take calcium supplements, including calcium-based antacids, while you are taking Phoslyra. Also, you should decrease or stop vitamin D therapy while you are taking Phoslyra. Tell your doctor if you experience constipation, loss of appetite, nausea, vomiting, confusion, or loss of consciousness.
Phoslyra contains maltitol and can cause a laxative effect, especially if this medication is taken with other products containing maltitol.
Follow-up with your doctor regularly to monitor your blood calcium and phosphorus levels while you are taking Phoslyra.
Who should not take Phoslyra?Do not take Phoslyra if you are allergic to it or any of its ingredients, or if you have high blood calcium levels.
What should I tell my doctor before I take the first dose of Phoslyra?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Phoslyra. Also, talk to your doctor about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The recommended starting dose is 10 milliliters (mL) of oral solution with each meal. Your doctor may adjust your dose based on your blood phosphorus levels.
How should I take Phoslyra?Take Phoslyra exactly as prescribed by your doctor. You can take Phoslyra with each meal. You should maintain your prescribed diet.
If you are taking certain oral antibiotics (such as ciprofloxacin or tetracycline), take the antibiotic 1 hour before or 3 hours after you take Phoslyra.
What should I avoid while taking Phoslyra?Do not take calcium supplements, including calcium-based antacids, while you are taking Phoslyra.
What are possible food and drug interactions associated with Phoslyra?If Phoslyra is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Phoslyra with the following: calcium-based antacids, certain oral antibiotics, digoxin, or other medicines containing maltitol.
What are the possible side effects of Phoslyra?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: diarrhea, dizziness, high blood calcium levels, nausea, swelling, vomiting, weakness
Can I receive Phoslyra if I am pregnant or breastfeeding?The effects of Phoslyra during pregnancy and breastfeeding are unknown. Phoslyra can be found in your breast milk if you take it during breastfeeding. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Phoslyra?If you miss a dose of Phoslyra, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
How should I store Phoslyra?Store at room temperature.