Plavix

Generic Name: Clopidogrel

  • What is Plavix?

    Plavix is a blood thinner used to treat people who have recently had a heart attack, stroke, or disease of the arteries; this drug will reduce the probability of experiencing these events again.

  • What is the most important information I should know about Plavix?

    Plavix increases the risk of bleeding. You may bruise or bleed more easily, and it may take longer than usual to stop bleeding. However, prolonged or excessive bleeding, or bloody stool or urine, is not normal; contact your doctor right away if this occurs. Taking Plavix with aspirin may increase the risk of bleeding in people with a history of recent stroke. Consult your doctor if you are going to have surgery and make your surgeon or dentist aware that you are taking Plavix.

    Thrombotic thrombocytopenic purpura (TTP) has been reported in people being treated with Plavix. TTP is a rare but serious condition in which blood clots form in the blood vessels, potentially blocking blood supply to the organs. TTP feels like the flu, with symptoms such as fever, tiredness, and aching joints. Seek medical help immediately if you experience extreme skin paleness, purple skin patches, or yellowing of the skin or eyes.

    It is important to take Plavix as directed. Avoid lapses in therapy.

  • Who should not take Plavix?

    Do not take Plavix if you are allergic to any of its ingredients.

    Plavix should not be used in patients with active bleeding, such as stomach ulcer or brain bleeding.

  • What should I tell my doctor before I take the first dose of Plavix?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Plavix. Also, talk to your doctor about your complete medical history, especially if you have a stomach ulcer or any other type of internal bleeding, if you have kidney problems, or if you will be having surgery or dental work. It is recommended that you stop taking Plavix 5 days before the scheduled surgery.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Disease of the Arteries of the Heart

    Adults: The recommended daily dose of Plavix is a single starting dose of 300 milligrams (mg) followed by 75 mg once a day. Aspirin (75-325 mg once a day) should be started and continued in combination with Plavix.

    Recent Heart Attack, Stroke, or Peripheral Arterial Disease (arteries away from your heart)

    Adults: The recommended daily dose of Plavix is 75 mg once a day.

  • How should I take Plavix?

    Plavix can be taken with or without food.

  • What should I avoid while taking Plavix?

    Avoid aspirin or aspirin-containing products while taking Plavix unless approved by your doctor.

  • What are possible food and drug interactions associated with Plavix?

    If Plavix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Plavix with the following: nonsteroidal anti-inflammatory drugs (NSAIDs), omeprazole, or warfarin.

  • What are the possible side effects of Plavix?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: bruising or bleeding easily

  • Can I receive Plavix if I am pregnant or breastfeeding?

    The effects of Plavix during pregnancy are unknown. Plavix may pass into breast milk. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Plavix?

    If you miss a dose of Plavix, take it as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take your next regular dose. Do not take two doses at once.

  • How should I store Plavix?

    Store at room temperature.

Meet the Pharmacists

I'm Shereen A. Gharbia, PharmD. Welcome to PDR Health!

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