Generic Name: Dexmedetomidine

  • What is Precedex?

    Precedex is a medicine used for sedation in people who are mechanically ventilated in an intensive care setting. It is also used for short-term sedation in people before or during surgical procedures. Precedex is administered intravenously (through a vein in your arm).

  • What is the most important information I should know about Precedex?

    Precedex will only be given to you by a trained health care professional, and you will be continuously monitored while on this medication.

    Precedex can cause a temporary increase in your blood pressure after starting the infusion. Precedex can also cause a decrease in blood pressure, abnormally slow heartbeat, or sudden heart problems. Tell your doctor if you have any heart problems, diabetes, or high blood pressure.

    Some people receiving Precedex can be arousable and alert when they are stimulated. This does not mean this medication is not working.

    After you stop receiving Precedex, you can experience withdrawal symptoms. If you receive Precedex for more than 6 hours, tell your doctor if you develop nervousness, agitation, or headaches that can occur for up to 48 hours. In addition, within 48 hours after the administration of Precedex, you can experience abdominal pain, confusion, constipation, diarrhea, dizziness, lightheadedness, salt cravings, sweating, weakness, or weight loss. Tell your doctor if you experience any of these symptoms.

    If you receive Precedex for more than 24 hours, you can develop tolerance or a sudden decrease in your response to this medication. This can lead to an increased incidence of dose-related side effects, especially if your doctor increases your Precedex dose.

  • Who should not take Precedex?

    Your doctor will not administer Precedex to you if you are allergic to it or any of its ingredients.

  • What should I tell my doctor before I take the first dose of Precedex?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Precedex. Also, talk to your doctor about your complete medical history, especially if you have liver disease, heart problems, diabetes, high blood pressure, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you based on your condition.

  • How should I take Precedex?

    Your doctor will administer Precedex to you in a hospital setting.

  • What should I avoid while taking Precedex?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Precedex?

    If Precedex is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior to treatment with Precedex: narcotic painkillers (such as oxycodone) or other medications that make you sleepy.

  • What are the possible side effects of Precedex?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: agitation, breathing problems, changes in your blood pressure, dry mouth, fever, irregular or slow heartbeat, nausea, vomiting

  • Can I receive Precedex if I am pregnant or breastfeeding?

    The effects of Precedex during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Precedex?

    Precedex should be given under special circumstances determined by your doctor.

  • How should I store Precedex?

    Your doctor will store this medication for you.