Prevacid

Generic Name: Lansoprazole

  • What is this medication and its most common uses?

    Prevacid is a medicine known as a proton pump inhibitor (PPI) that is used to treat stomach ulcers and treat and prevent stomach ulcers associated with nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen). Prevacid is also used to treat and maintain duodenal ulcers (ulcers in the upper intestine), and erosive esophagitis (inflammation of the esophagus [the tube that connects your mouth and stomach]). In addition, Prevacid is used to treat heartburn and other symptoms associated with gastroesophageal reflux disease (GERD); for long-term treatment of conditions where your stomach makes too much acid, such as Zollinger-Ellison syndrome; and with other medicines to eliminate the bacteria that often cause ulcers (known as Helicobacter pylori). Prevacid is available as capsules and as orally disintegrating tablets.

  • What should I know when beginning and continuing on this medication?

    How does this medication work?

    Prevacid is a delayed-release medicine (releases medicine into your body at a later time from when you take it). It works by reducing the acid in your stomach.

    What are the beneficial effects of this medication and when should I begin to have results?

    What:

    GERD/Erosive Esophagitis: Prevacid may help heal acid-related damage to the lining of your esophagus and relieve symptoms such as heartburn.

    Duodenal Ulcers: Prevacid may help heal and reduce the frequency and severity of pain associated with duodenal ulcers, and may help reduce the amount of antacids you take.

    Stomach Ulcers: Prevacid may help heal stomach ulcers.

    Stomach Ulcers Associated with NSAID Use: Prevacid may help heal and prevent stomach ulcers from coming back with long-term NSAID use.

    H. pylori Infection: When used in combination with other medicines, Prevacid may cure this infection and reduce your risk of having another ulcer.

    Conditions Causing Increased Stomach Acid Production: Prevacid may reduce the acid produced in your stomach, thereby relieving symptoms associated with this condition.

    When:

    GERD: Prevacid may start reducing the frequency and severity of daytime and nighttime heartburn after 1 week of therapy.

    Erosive Esophagitis: Studies show that after 4 weeks of therapy, Prevacid can heal damage to the lining of esophagus in 80-95% of people. Less recurrence was also seen when Prevacid was taken over a 12-month period.

    Duodenal Ulcers: Prevacid is shown to heal duodenal ulcers after 2-4 weeks of therapy and can prevent recurrence.

    Stomach Ulcers: After 4 weeks of therapy, studies show Prevacid significantly helps heal stomach ulcers.

    Stomach Ulcers Associated with NSAID Use: Studies show that people treated with Prevacid remained ulcer free and it can heal stomach ulcers, when evaluated at 8 weeks of therapy.

    H. pylori Infection: When used in combination with other medicines in a 14-day treatment course, Prevacid has been shown to keep 80-90% of people infection-free at 4 weeks after completing therapy.

    Conditions Causing Increased Stomach Acid Production: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Prevacid exactly as your healthcare provider has prescribed.

    How do I know it is working?

    You may start to notice a reduction in the severity or frequency of your heartburn. This is a good indicator that your medication is working. Your healthcare provider will ask you questions from time to time to assess how well your heartburn and/or pain is controlled and to check for improvement of your condition.

  • What are the possible side effects of this medication?

    The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

    More common side effects may include: diarrhea, abdominal pain, nausea, constipation.

    Less common side effects may include:

    Diarrhea that does not go away.

    Fractures of the hip, wrist, or spine if you take multiple doses a day for long periods.

    Low blood magnesium levels with symptoms such as seizures, irregular heartbeat, jerking movements or shaking, muscle weakness, spasms of your hands and feet, cramps or muscle aches, or spasm of your voice box.

  • Who should not take this medication?

    Do not take Prevacid if you are allergic to it or any of its ingredients.

  • What should I tell my healthcare provider before I take the first dose of this medication?

    Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Prevacid. Also, talk to your healthcare provider about your complete medical history, especially if you have low blood magnesium levels, liver problems, or phenylketonuria (an inability to process phenylalanine, a protein in your body), or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

    Erosive Esophagitis

    Adults: The recommended dose is 30 milligrams (mg) once a day for up to 8 weeks. Depending on your response, your healthcare provider may suggest another 8 weeks of treatment.

    Adolescents 12-17 years: The recommended dose is 30 mg once a day for up to 8 weeks.

    Children 1-11 years: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.

    Maintenance of Healing of Erosive Esophagitis

    Adults: The recommended dose is 15 mg once a day.

    Treatment of GERD

    Adults and adolescents 12-17 years: The recommended dose is 15 mg once a day for up to 8 weeks.

    Children 1-11 years: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.

    Prevention of Duodenal Ulcer Due to H. pylori Infection

    Adults: This treatment involves taking two or three different medications. The usual dose for the dual therapy is: Prevacid 30 mg three times a day for 14 days and amoxicillin 1000 mg three times a day for 14 days. The usual dose for the triple therapy is: Prevacid 30 mg twice a day for 10 or 14 days, amoxicillin 1000 mg twice a day for 10 or 14 days, and clarithromycin 500 mg twice a day for 10 or 14 days.

    Treatment or Prevention of Duodenal Ulcer

    Adults: The recommended dose is 15 mg once a day. Your healthcare provider may suggest continuing treatment to prevent a relapse.

    Treatment of Stomach Ulcer Due to NSAIDs

    Adults: The recommended dose is 30 mg once a day for 8 weeks. Risk Reduction of Stomach Ulcer Due to NSAIDs

    Adults: The recommended dose is 15 mg once a day for up to 12 weeks.

    Treatment of Stomach Ulcer

    Adults: The recommended dose is 30 mg once a day for up to 8 weeks.

    Conditions Causing Increased Stomach Acid Production (Such as Zollinger-Ellison Syndrome)

    Adults: The recommended dose is 60 mg once a day. Your healthcare provider might prescribe a different dose or duration based on your condition.

  • How should I take this medication?

    Take Prevacid exactly as prescribed by your healthcare provider.

    Take Prevacid before food. Swallow capsules whole. Do not break, cut, or chew the capsules.

    If you cannot swallow capsules, open the capsule and sprinkle its contents on a tablespoon of applesauce, ENSURE pudding, cottage cheese, yogurt, or strained pears. Swallow right away. You can also sprinkle the capsule contents into 60 milliters (about 1/4 cup) of apple juice, orange juice, or tomato juice, stir, and then swallow right away. To make sure the entire dose is taken, rinse the glass with 1/2 cup or more of juice to get out any leftover granules. Swallow the juice right away.

    If you are taking Prevacid orally disintegrating tablets, put the tablet under your tongue and let it dissolve, with or without water. Do not chew, crush, cut, or break the tablet. Swallow after the tablet dissolves. The tablet usually dissolves in less than 1 minute.

    Please review the instructions that came with your prescription on how to properly take Prevacid.

  • What should I avoid while taking this medication?

    Do not change your dose or stop taking Prevacid without first talking to your healthcare provider.

  • What are the possible food and drug interactions associated with this medication?

    If Prevacid is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Prevacid with the following: ampicillin, atazanavir, digoxin, ketoconazole, methotrexate, iron-containing products, sucralfate, tacrolimus, theophylline, or warfarin.

  • May I receive this medication if I am pregnant or breastfeeding?

    The effects of Prevacid during pregnancy are unknown. Do not breastfeed while you are taking Prevacid. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of this medication?

    If you miss a dose of Prevacid, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store this medication?

    Store at room temperature.

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