Generic Name: Cholestyramine

  • What is Prevalite?

    Prevalite is a cholesterol-lowering medicine used, in addition to an appropriate diet, to reduce "bad" cholesterol called low density lipoprotein (LDL). Prevalite is also used to treat itching associated with partial biliary obstruction (blockage in the tubes that carry bile from the liver to the gallbladder and small intestine).

  • What is the most important information I should know about Prevalite?

    Long-term use of Prevalite can cause bleeding problems or acidosis (a condition in which there is too much acid in the body) caused by a high level of chloride in your blood.

    Prevalite can cause or worsen constipation, which can aggravate existing hemorrhoids (swollen and inflamed veins in the anus and lower rectum). Drink plenty of fluids to reduce your risk of constipation.

    Prevalite can reduce the absorption of other medications you take by mouth. Take other medications at least 1 hour before or 4-6 hours after Prevalite.

    Sipping or holding the mixed Prevalite suspension in your mouth for prolonged periods can lead to changes in the surface of your teeth, resulting in discoloration, erosion (wearing away of the surface) of your enamel, or decay. You must maintain good oral hygiene.

  • Who should not take Prevalite?

    Do not take Prevalite if you are allergic to it or any of its ingredients, or if you have a complete biliary obstruction.

  • What should I tell my doctor before I take the first dose of Prevalite?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Prevalite. Also, talk to your doctor about your complete medical history, especially if you have phenylketonuria (an inability to process phenylalanine, a protein in your body), diabetes, hypothyroidism (an underactive thyroid gland), kidney or liver impairment, alcoholism, blood disorders, complete biliary obstruction, stomach or intestinal problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The recommended starting dose is 1 packet or 1 level scoopful 1-2 times a day.

    Children: Your doctor will prescribe the appropriate dose for your child, based on their weight.

  • How should I take Prevalite?

    Take Prevalite exactly as prescribed by your doctor.

    Drink plenty of fluids and mix each packet or dose of Prevalite in at least 2-3 ounces of fluid before taking. Stir to a uniform consistency. You can also mix Prevalite with highly fluid soups or pulpy fruits with high moisture content, such as applesauce or crushed pineapple.

    Please review the instructions that came with your prescription on how to properly prepare and use Prevalite.

  • What should I avoid while taking Prevalite?

    Do not take Prevalite in its dry form. Always mix Prevalite with water or other fluids before taking it.

    Do not sip or hold the suspension in your mouth for prolonged periods.

  • What are possible food and drug interactions associated with Prevalite?

    If Prevalite is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Prevalite with the following: blood thinners (such as warfarin), digitalis, diuretics (water pills), estrogens, penicillin G, phenobarbital, phenylbutazone, phosphate supplements, progestins, propranolol, spironolactone, tetracycline, or thyroid and thyroxine preparations.

  • What are the possible side effects of Prevalite?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal discomfort or pain, bleeding problems, constipation, diarrhea, gas, indigestion, irritation of your tongue or around your anus, loss of appetite, nausea, osteoporosis (thin, weak bones), rash, skin irritation, vomiting

  • Can I receive Prevalite if I am pregnant or breastfeeding?

    The effects of Prevalite during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Prevalite?

    If you miss a dose of Prevalite, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Prevalite?

    Store at room temperature.