Generic Name: Rifapentine

  • What is Priftin?

    Priftin is a medicine used to treat tuberculosis caused by the bacteria Mycobacterium tuberculosis. Priftin is used in combination with one or more antituberculosis medications.

  • What is the most important information I should know about Priftin?

    It is important that you take the full course of Priftin therapy and not miss any doses of the other prescribed medications.

    Priftin can produce a reddish coloration of your urine, sweat, saliva, tears, and breast milk, and can permanently stain your contact lenses or dentures.

    Priftin can cause severe liver impairment. Your risk can increase if you drink alcohol. Your doctor will monitor your liver function and blood counts. Tell your doctor immediately if you experience tiredness, weakness, loss of appetite, nausea, or vomiting.

    Priftin can cause diarrhea or colitis (inflammation of the colon). This can happen a couple of months after receiving the last dose of Priftin. Tell your doctor immediately if you experience diarrhea or colitis.

    Priftin can reduce the effectiveness of hormonal birth control. Talk to your doctor about changing to a non-hormonal method of birth control while you are taking Priftin.

  • Who should not take Priftin?

    Do not take Priftin if you are allergic to it or any of its ingredients. Also, do not take Priftin if you have porphyria (a blood disorder that interferes with how your body produces heme, which is the oxygen-carrying component of your red blood cells).

  • What should I tell my doctor before I take the first dose of Priftin?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Priftin. Also, talk to your doctor about your complete medical history, especially if you have a history of alcohol abuse, blood disorders, have HIV or AIDS, liver or kidney problems, nutritional deficiency, porphyria, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥12 years: The recommended dose is 600 milligrams (mg) (4 tablets) twice a week for 2 months, followed by 600 mg once a week for 4 months.

  • How should I take Priftin?

    Take Priftin exactly as prescribed by your doctor. Do not take extra doses or take more often without asking your doctor.

    Take Priftin in combination with the other antituberculosis medications that your doctor prescribed.

    Take Priftin with food and at an interval of no less than 3 consecutive days (72 hours).

  • What should I avoid while taking Priftin?

    Do not drink alcohol while you are taking Priftin.

  • What are possible food and drug interactions associated with Priftin?

    If Priftin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Priftin may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.

  • What are the possible side effects of Priftin?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, anemia, blood disorders, discoloration of your body fluids, faintness or dizziness, fever, high bilirubin levels, infectious diarrhea, liver problems, loss of appetite, low blood sugar, low white blood cell counts, red spots on skin, swelling of your joints, trouble urinating, unusual bleeding or bruising, urinary tract infections, yellowing of your skin or whites of your eyes

  • Can I receive Priftin if I am pregnant or breastfeeding?

    Priftin may cause harm to your unborn baby if you take it during pregnancy. The effects of Priftin while breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Priftin?

    If you miss a dose of Priftin, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

  • How should I store Priftin?

    Store at room temperature.