Primaxin IM

Generic Name: Cilastatin

  • What is Primaxin IM?

    Primaxin intramuscular (IM) (injected into the muscle) is an antibiotic used to treat certain bacterial infections of the respiratory (lung) or genital tract, skin, or abdomen. It may also be used to treat other bacterial infections, as determined by your doctor.

  • What is the most important information I should know about Primaxin IM?

    Do not use Primaxin IM if you are allergic to it or any of its ingredients. If you are allergic to similar antibiotics (such as ceftriaxone, cephalexin, or penicillin), it is possible for you to have an allergic reaction to this medication. Tell your doctor immediately if you receive Primaxin IM and develop a rash, swelling, or difficulty breathing.

    Primaxin IM can cause diarrhea or colitis (inflammation of the colon). This can occur a couple of months after receiving the last dose of Primaxin IM. Tell your doctor immediately if you have diarrhea or colitis.

    Primaxin IM can cause seizures and other central nervous system (CNS) adverse experiences, especially when it is given at a high dose. These problems are more commonly seen when people with kidney problems use Primaxin IM.

  • Who should not take Primaxin IM?

    Your doctor will not administrate Primaxin IM to you if you are allergic to it, any of its ingredients, similiar antibiotics, or local anesthetics (such as lidocaine).

    Your doctor will not administrate Primaxin IM to you to treat viral infections, such as the common cold.

  • What should I tell my doctor before I take the first dose of Primaxin IM?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Primaxin IM. Also, talk to your doctor about your complete medical history, especially if you have allergies, CNS disorders (such as a history of seizures), kidney disease, or liver problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥12 years: Your doctor will administer the appropriate dose for you based on the type and severity of your infection.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

  • How should I take Primaxin IM?

    Your doctor will administer Primaxin IM for you.

  • What should I avoid while taking Primaxin IM?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Primaxin IM?

    If Primaxin IM is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior treatment with Primaxin IM: divalproex sodium, probenecid, or valproic acid.

  • What are the possible side effects of Primaxin IM?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, colitis, diarrhea, kidney or liver problems, nausea, pain at the injection site, seizures, vomiting

  • Can I receive Primaxin IM if I am pregnant or breastfeeding?

    The effects of Primaxin IM during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Primaxin IM?

    Primaxin IM should be given under special circumstances determined by your doctor.

  • How should I store Primaxin IM?

    Your doctor will store this medication for you.