Primaxin IV

Generic Name: Cilastatin

  • What is Primaxin IV?

    Primaxin intravenous (IV) (administered through a vein in your arm) is an antibiotic used to treat certain bacterial infections of the respiratory (lung), urinary, or genital tracts; and skin, bone, joint, blood, heart, or abdominal infections. It may also be used to treat other bacterial infections, as determined by your doctor.

  • What is the most important information I should know about Primaxin IV?

    Your doctor will not administer Primaxin IV to you if you are allergic to it or any of its ingredients. If you are allergic to similar antibiotics (such as ceftriaxone, cephalexin, or penicillin), it is possible for you to have an allergic reaction to this medication. Tell your doctor immediately if you receive Primaxin IV and develop a rash, swelling, or difficulty breathing.

    Primaxin IV can cause diarrhea or colitis (inflammation of the colon). This can occur a couple of months after receiving the last dose of Primaxin IV. Tell your doctor immediately if you have diarrhea or colitis.

    Primaxin IV can cause seizures and other central nervous system (CNS) adverse experiences (such as confusional states), especially when it is given at a high dose. These problems are more commonly seen when people with kidney problems use Primaxin IV.

  • Who should not take Primaxin IV?

    Your doctor will not administer Primaxin IV to you if you are allergic to it, any of its ingredients, or similiar antibiotics.

    Your doctor will not administer Primaxin IV to you to treat viral infections, such as the common cold.

  • What should I tell my doctor before I take the first dose of Primaxin IV?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Primaxin IV. Also, talk to your doctor about your complete medical history, especially if you have allergies, CNS disorders (such as a history of seizures), kidney disease, or liver problems.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Your doctor will administer the appropriate dose for you based on your condition.

    If you have kidney impairment, your doctor will adjust your dose appropriately.

    Children ≥3 months: Your doctor will administer the appropriate dose for your child, based on their weight.

  • How should I take Primaxin IV?

    Your doctor will administer Primaxin IV to you.

  • What should I avoid while taking Primaxin IV?

    Do not miss your scheduled follow-up appointments with your doctor.

  • What are possible food and drug interactions associated with Primaxin IV?

    If Primaxin IV is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior treatment with Primaxin IV: divalproex sodium, ganciclovir, probenecid, or valproic acid.

  • What are the possible side effects of Primaxin IV?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: allergic reactions, colitis, diarrhea, dizziness, fever, injection-site reactions, itchiness, kidney or liver problems, low blood pressure, nausea, seizures, vomiting

  • Can I receive Primaxin IV if I am pregnant or breastfeeding?

    The effects of Primaxin IV during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Primaxin IV?

    Primaxin IV should be given under special circumstances determined by your doctor.

  • How should I store Primaxin IV?

    Your doctor will store this medication for you.