Proquin XR

Generic Name: Ciprofloxacin

  • What is Proquin XR?

    Proquin XR is an antibiotic in the class known as quinolones that is used to treat adults with uncomplicated urinary tract infections (also known as bladder infections) caused by bacteria.

  • What is the most important information I should know about Proquin XR?

    Fluoroquinolones, including Proquin XR, are associated with an increased risk of tendinitis (inflammation or irritation of a tendon) and tendon rupture in all ages. The risk is greater in older patients, usually >60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, and lung transplants.

    Pseudomembranous colitis (an infection of the colon resulting in diarrhea) has been reported with nearly all antibacterial agents, including Proquin XR, and may range in severity from mild to life-threatening. Therefore, it is important to tell your doctor if you experience diarrhea during or after treatment with antibacterial agents such as Proquin XR.

    Stop taking Proquin XR and notify your doctor immediately if you experience a severe allergic reaction (characterized by rash; difficulty breathing; hives; swelling of the lips, tongue, or face; or throat tightening), fever, back pain, fainting spells, abnormal heartbeat or heart rhythm changes, seizures, severe skin rash, a sunburn-like reaction or skin eruption or changes in sensation and possible nerve damage characterized by pain, burning, tingling, numbness, and weakness.

    Proquin XR is only used to treat bacterial infections and will not work if taken for a viral infection, such as a common cold.

    Skipping doses or not completing the full course of Proquin XR therapy may decrease the effectiveness of the treatment and increase the likelihood that bacteria will develop resistance. If the bacteria develop resistance, they may not be treatable by Proquin XR or other antibacterial drugs in the future.

  • Who should not take Proquin XR?

    Do not take Proquin XR if you are allergic to, or have ever had a severe reaction to, ciprofloxacin or to any other quinolone antibiotics.

  • What should I tell my doctor before I take the first dose of Proquin XR?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Proquin XR. Also, talk to your doctor about your complete medical history, especially if you have tendon problems, have central nervous system problems (such as epilepsy), have nerve problems, if anyone in your family has an irregular heartbeat (especially a condition called QT prolongation, have a history of seizures, have kidney problems, have low blood potassium (hypokalemia), have rheumatoid arthritis (RA) or other history of joint problems, have trouble swallowing pills, are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Proquin XR should be taken once a day for 3 days shortly after a main meal of the day, preferably the evening meal. Proquin XR does not work as well if you take it without a meal. Your exact dosage of this medication will be prescribed by your doctor.

  • How should I take Proquin XR?

    You should try to take Proquin XR at about the same time each day.

    Take Proquin XR at least 4 hours before or 2 hours after antacids containing magnesium or aluminum, sucralfate, didanosine, chewable/buffered tablets or pediatric powder, iron, and multivitamin preparations containing zinc.

    Take Proquin XR exactly as prescribed by your doctor. Swallow whole with plenty of fluids. Do not split, crush, or chew.

  • What should I avoid while taking Proquin XR?

    Avoid taking Proquin XR with dairy products (like milk or yogurt) or calcium-fortified juices alone.

    It is important to limit your exposure to sun and artificial sunlight. Proquin XR tablets can make your skin sensitive to sun, sunlamps, and tanning beds. Consequently, this may cause you to develop a severe sunburn, blisters, or swelling of your skin. Notify your physician immediately if any of these symptoms occur and wear protective clothing and sunscreen when you are exposed to sunlight.

    Proquin XR may cause dizziness or lightheadedness. It is important to avoid performing potentially hazardous tasks (eg, driving, operating machinery, engaging in activities that require mental alertness) until you are used to the effects of Proquin XR.

  • What are possible food and drug interactions associated with Proquin XR?

    If Proquin XR is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Proquin XR with the following: antacids; antiarrhythmics; antipsychotics; caffeine; corticosteroids; cyclosporine; didanosine; diuretics; glyburide; methotrexate; metoclopramide; multivitamins or other products that contain magnesium, calcium, iron or zinc; nonsteroidal anti-inflammatory drugs (NSAIDs); omeprazole; phenytoin; probenecid; sucralfate; theophylline; tricyclic antidepressants; or warfarin.

  • What are the possible side effects of Proquin XR?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: yeast infection, inflamed nose and throat, headache, feeling an urgent need to urinate

  • Can I receive Proquin XR if I am pregnant or breastfeeding?

    The effects of Proquin XR during pregnancy and breastfeeding are unknown. Talk with your doctor before taking this drug if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Proquin XR?

    If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip it and resume your scheduled dose. Do not take two doses at once. Do not take more than one Proquin XR tablet a day, even if you miss a dose.

  • How should I store Proquin XR?

    Store at room temperature.

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