What is Provigil?Provigil is used to improve awakeness in adults who are very sleepy due to shift work sleep disorder (SWSD), obstructive sleep apnea/hypopnea syndrome (OSAHS, stopping breathing temporarily during sleep), or narcolepsy (a sleep disorder characterized by excessive daytime sleepiness).
What is the most important information I should know about Provigil?Provigil is a controlled substance because it can be abused or lead to dependence. Keep Provigil in a safe place to prevent misuse and abuse.
Provigil may cause a serious rash or serious allergic reaction. Stop Provigil and call your doctor right away or get emergency treatment if you have any of the following: skin rash or skin that blisters and peels; hives; sores in your mouth; swelling of your face, eyes, lips, tongue, or throat; trouble swallowing or breathing; or hoarse voice.
Provigil may cause serious side effects, including heart problems such as chest pain and mental problems such as depression, anxiety, hallucinations, mania, thoughts of suicide and aggression. If you notice any of these problems, stop taking Provigil and call your doctor or get emergency help.
This drug will not cure any sleep disorder, but it may help improve wakefulness. Provigil does not take the place of getting enough sleep. Follow your doctor's advice about good sleep habits and using other treatments.
Provigil is used along with other medical treatments for SWSD, OSAHS, or narcolepsy and is not a replacement for a continuous positive airway pressure (CPAP) machine (a machine that helps your breathing during sleep) in people with OSAHS. It is important that you continue to use your CPAP machine while sleeping.
Who should not take Provigil?Do not take Provigil if you are allergic to any of its ingredients or if you have had a rash or allergic reaction to armodafinil, the active ingredient in Nuvigil.
What should I tell my doctor before I take the first dose of Provigil?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Provigil. Also, talk to your doctor about your complete medical history, especially if you have ever had a heart attack, mental health problems (such as psychosis), high blood pressure, heart problems, liver or kidney problems, or a history of drug or alcohol addiction. You should also tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
Tell the doctor if you use a hormonal birth control method (including birth control pills, shots, implants, patches, vaginal rings, and IUDs); Provigil can interfere with these types of birth control. Women using hormonal birth control with Provigil may have a higher chance of getting pregnant while taking Provigil and for 1 month after stopping the drug.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) and Narcolepsy
Adults: The recommended dose is 150 milligrams (mg) or 250 mg given as a single dose in the morning.
Shift Work Sleep Disorder (SWSD)
Adults: The recommended dose is 150 mg given daily approximately 1 hour before the start of a work shift.
The usual dose of Provigil for people with severe liver problems is 100 mg once daily.
How should I take Provigil?Take Provigil exactly as prescribed by your doctor. Your doctor will tell you the right time of day to take Provigil. You can take Provigil with or without food.
If you take Provigil too close to your bedtime, you may find it harder to go to sleep.
What should I avoid while taking Provigil?Avoid driving or operating hazardous machinery until you know how Provigil affects you.
Avoid drinking alcohol while taking Provigil.
What are possible food and drug interactions associated with Provigil?If Provigil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Provigil with the following: antidepressants, carbamazepine, clomipramine, cyclosporine, diazepam, itraconazole, ketoconazole, MAOIs, methylphenidate, birth control pills and hormonal implants, phenobarbital, phenytoin, propranolol, rifampin, theophylline, and warfarin.
What are the possible side effects of Provigil?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: headache, nausea, nervousness, stuffy nose, diarrhea, back pain, anxiety, trouble sleeping, dizziness, upset stomach
Can I receive Provigil if I am pregnant or breastfeeding?The effects of Provigil during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Provigil?Take a missed dose as soon as you remember. If it is close to bedtime, skip the missed dose and go back to your regular schedule. Do not take two doses at once.
How should I store Provigil?Store at room temperature.
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