Quinidine sulfate

  • What is Quinidine sulfate?

    Quinidine sulfate is used to correct certain types of irregular heart rhythms and to slow an abnormally fast heartbeat. It can also be used to treat malaria.
  • What is the most important information I should know about Quinidine sulfate?

    Quinidine sulfate is associated with an increased risk of death when used to treat non-life-threatening irregular heartbeat. This risk may be greater if you have structural heart disease.

    Quinidine sulfate is reserved for certain kinds of dangerously rapid heart irregularities. It works well for some people, providing them with significant relief of symptoms. However, it has not been shown to improve chances of long-term survival. Under certain conditions (slow heart rate, low potassium or magnesium levels), quinidine sulfate may cause certain types of heart irregularity. It may cause the condition known as heart block, and should be used with caution if you have partial heart block.

  • Who should not take Quinidine sulfate?

    Do not take quinidine sulfate if you have ever had an allergic reaction to quinidine. Also avoid quinidine sulfate if quinine or quinidine causes you to bruise easily.

    Quinidine sulfate is prescribed for specific types of heart irregularity, and should be avoided when other irregularities are present. It should also be avoided in patients whose heart rhythms are dependent on a pacemaker. It could also prove harmful if you have myasthenia gravis (abnormal muscle weakness) or a similar condition.

  • What should I tell my doctor before I take the first dose of Quinidine sulfate?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with quinidine sulfate. Also, talk to your doctor about your complete medical history, especially if you have myasthenia gravis, kidney or liver disease, congestive heart failure, heart block, QT prolongation, or other heart problems; low blood pressure, high or low blood calcium levels, decreased blood platelets, or digitalis intoxication.
  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: Depending on your individual goals of therapy, your doctor will prescribe a dose specific for your condition.

  • How should I take Quinidine sulfate?

    Take quinidine sulfate exactly as prescribed. If you experience stomach upset you may take this medication with food.
  • What should I avoid while taking Quinidine sulfate?

    Avoid activities that require mental alertness until you know how your body reacts to this medication. Try to avoid antacids, grapefruit juice, and herbal products; speak to your doctor before using them with this medication.
  • What are possible food and drug interactions associated with Quinidine sulfate?

    If quinidine sulfate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining quinidine sulfate with the following: amiodarone, antidepressants, antacids containing magnesium, antispasmodic drugs, aspirin, beta-blocking blood pressure medications, blood thinners, diuretics, cimetidine, codeine, decamethonium, digoxin, digitoxin, diltiazem, disopyramide, felodipine, grapefruit juice, haloperidol, hydrocodone, ketoconazole, major tranquilizers, mexiletine, nicardipine, nifedipine, nimodipine, phenobarbital, phenytoin, physostigmine, procainamide, reserpine, rifampin, sodium bicarbonate, sucralfate, thiazide diuretics, verapamil

    A decrease in your salt intake can lead to a higher blood level of quinidine sulfate. Try to keep the salt in your diet constant.

  • What are the possible side effects of Quinidine sulfate?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, change is sleep habits, chest pain, diarrhea, eye problems, headache, hepatitis, light headedness, inflammation of the esophagus, loss of appetite, nausea, rash, vomiting, weakness

    Another possible side effect is a sensitivity reaction called cinchonism. Symptoms include blurred or double vision, confusion, delirium, diarrhea, headache, intolerance to light, hearing loss, ringing in the ears, vertigo, and vomiting.

  • Can I receive Quinidine sulfate if I am pregnant or breastfeeding?

    There are no adequate studies on the effects of quinidine sulfate during pregnancy, so it should be given to a pregnant woman only if clearly needed. Tell your doctor immediately if you are pregnant or plan to become pregnant.

    Quinidine sulfate appears in breast milk and can affect a nursing infant. If this drug is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

  • What should I do if I miss a dose of Quinidine sulfate?

    Take it as soon as you remember. However, if it is within 4 hours of your next dose, skip the missed dose and continue with your normal dosing schedule. Do not take 2 doses at once.
  • How should I store Quinidine sulfate?

    Store at room temperature in a tightly closed container, away from light.