What is Regranex?Regranex is a topical gel (applied directly on the skin) used with other ulcer care practices (such as good wound care) to treat diabetic sores (ulcers) of your legs or feet that are deeper than just your skin, if you have good blood supply to your lower legs and feet.
What is the most important information I should know about Regranex?Regranex is for external use only. Do not use it in your mouth, eyes, or vagina.
If you use more than 3 tubes of Regranex, you can have an increased risk of death from cancer. Tell your doctor if you already have cancer.
Regranex can cause allergic skin reactions or irritation when it is applied. Tell your doctor immediately if this occurs.
Who should not take Regranex?Do not use Regranex if you are allergic to it or any of its ingredients, or if you have skin cancer in the area where you apply this medicine.
What should I tell my doctor before I take the first dose of Regranex?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Regranex. Also, talk to your doctor about your complete medical history, especially if you have allergies, cancer, or poor blood flow to your lower legs and feet, or are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults and adolescents ≥16 years: Apply to the affected area(s) once a day. The amount of gel to apply depends on the size of your ulcer.
How should I take Regranex?Apply Regranex exactly as prescribed by your doctor. Wash your hands thoroughly before applying Regranex gel. Squeeze the amount of Regranex needed for your ulcer on to a clean, firm, nonabsorbable surface, such as wax paper. You can use a clean cotton swab, tongue depressor, or other application aid to spread the gel in a thin even layer over the surface of the ulcer on your foot or leg. Cover the treated area with a saline-moistened gauze dressing. After about 12 hours, gently rinse the ulcer with saline or water to remove the rest of the gel. Cover the ulcer with a new saline-moistened gauze dressing. Do not apply any more Regranex for that day. Recap the tube tightly after each use.
What should I avoid while taking Regranex?Do not use Regranex in your mouth, eyes, or vagina.
Do not let the tip of the Regranex tube touch your ulcer or any other surface, as this can contaminate Regranex.
What are possible food and drug interactions associated with Regranex?No significant interactions have been reported with Regranex at this time. However, always tell your doctor about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
What are the possible side effects of Regranex?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: burning at the application site, red skin rash
Can I receive Regranex if I am pregnant or breastfeeding?The effects of Regranex during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Regranex?If you miss a dose of Regranex, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.
How should I store Regranex?Store in the refrigerator. Do not freeze.