Generic Name: Nabumetone

  • What is Relafen?

    Relafen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.

  • What is the most important information I should know about Relafen?

    Relafen may increase your risk of life-threatening heart or circulation problems, including heart attack or stroke, especially with long-term use, and may result in hospitalization and even death. These may occur without warning signs. Tell your doctor immediately if you experience chest pain, shortness of breath, or weakness.

    Relafen may cause stomach discomfort, and rarely, serious ulcers or internal bleeding can occur without warning and result in hospitalization or even death. Tell your doctor immediately if you experience stomach pain, indigestion, or bloody vomit or stools.

    Contact your doctor if you experience any changes in your vision, skin rash or blisters with fever, unexplained weight gain or fluid retention, yellowing of your skin or eyes, "flu-like" symptoms, difficulty breathing, or swelling of the face or throat while taking Relafen.

  • Who should not take Relafen?

    Do not take Relafen just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

    Do not take Relafen if you are sensitive to or have ever had an allergic reaction to Relafen, or if you have had asthma attacks, hives or other allergic reactions caused by aspirin or other NSAIDs.

  • What should I tell my doctor before I take the first dose of Relafen?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Relafen. Also, talk to your doctor about your complete medical history, especially if you have a history of heart attack, stroke, blood clot, heart disease, congestive heart failure, high blood pressure, a history of stomach ulcers or bleeding, liver or kidney disease, asthma, nasal polyps (non-cancerous growth in the nose), a bleeding or blood clotting disorder, asthma, fluid retention, or if you smoke or drink alcohol.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults: The usual starting dose is 1,000 milligrams (mg) taken as a single dose. Your dosage may be increased up to 2,000 mg per day, taken once daily or divided into two doses.

  • How should I take Relafen?

    Relafen can be taken with or without food. Take Relafen exactly as prescribed. Relafen should only be used at the lowest dose possible and for the shortest time needed.

  • What should I avoid while taking Relafen?

    Relafen may cause increased sensitivity to sunlight. Avoid prolonged exposure to sunlight.

    Do not drink alcohol while taking Relafen. Alcohol may increase the risk of stomach bleeding.

  • What are possible food and drug interactions associated with Relafen?

    If Relafen is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Relafen with the following: aspirin, ACE inhibitors, diuretics (water pills), lithium, methotrexate, other NSAIDs, warfarin.

  • What are the possible side effects of Relafen?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: abdominal pain, constipation, diarrhea, dizziness, fluid retention, gas, headache, indigestion, itching, nausea, rash, ringing in ears

  • Can I receive Relafen if I am pregnant or breastfeeding?

    The effects of Relafen during pregnancy and breastfeeding are unknown. Do not use Relafen in the last 3 months of your pregnancy. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Relafen?

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and go back to your regular schedule. Do not take two doses at once.

  • How should I store Relafen?

    Store at room temperature.

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I'm Beth Isaac, PharmD. Welcome to PDR Health!

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