Generic Name: Delavirdine

  • What is Rescriptor?

    Rescriptor is a medicine used in combination with at least two other anti-HIV medications to treat HIV (human immunodeficiency virus) infection (AIDS). Rescriptor is a type of medication called a non-nucleoside reverse transcriptase inhibitor (NNRTI).

  • What is the most important information I should know about Rescriptor?

    You must take Rescriptor with other HIV medications. Always stay on continuous HIV therapy to control your HIV infection and decrease HIV-related illnesses. Though Rescriptor can slow the progress of HIV, it is not a cure. Also, Rescriptor does not lower your chance of passing HIV to others through sexual contact or blood contamination. You may continue to develop infections and other complications associated with HIV.

    Rescriptor can cause changes or accumulation of body fat in your upper back and neck ("buffalo hump"), breast, and around the middle of your body. Loss of fat from your legs, arms, and face can also occur.

    Changes in your immune system can occur when you start taking Rescriptor. Your immune system can get stronger and begin to fight infections that have been hidden in your body for a long time. Call your doctor immediately if you start having new symptoms after starting Rescriptor.

    A common side effect of Rescriptor is a skin rash that occurs mainly on the upper body and upper arms, or sometimes on the neck and face. The rash usually occurs within 1-3 weeks after you start treatment, and it usually lasts less than 2 weeks. Stop taking Rescriptor and talk to your doctor immediately if you develop a severe rash with fever, blistering, sores in your mouth, redness or swelling of your eyes, or muscle and joint aches.

  • Who should not take Rescriptor?

    Do not take Rescriptor if you are allergic to it or any of its ingredients.

    Do not take Rescriptor if you are currently taking alprazolam, astemizole, carbamazepine, cisapride, dihydroergotamine, ergonovine, ergotamine, lovastatin, methylergonovine, midazolam, phenobarbital, phenytoin, pimozide, rifabutin, rifampin, simvastatin, terfenadine, triazolam, or St. John's wort.

  • What should I tell my doctor before I take the first dose of Rescriptor?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Rescriptor. Also, talk to your doctor about your complete medical history, especially if you have had or currently have liver or kidney problems, or are pregnant, plan to become pregnant, or are breastfeeding.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults and children ≥16 years: The recommended dose is two 200-milligram (mg) tablets or four 100-mg tablets 3 times a day.

  • How should I take Rescriptor?

    Take Rescriptor exactly as prescribed by your doctor. You can take Rescriptor with or without food. Do not change your dose or stop taking Rescriptor without first talking with your doctor.

    If you have trouble swallowing tablets, the 100-mg Rescriptor tablets can be dissolved in water. Place 4 tablets in at least 3 ounces of water and allow the tablets to sit in the water for a few minutes. Then, stir the water until the tablets have dissolved and drink the mixture immediately. Add a little more water, swirl, and then drink the rest of the mixture to be sure that you get all the medicine.

    The 200-mg tablets must be swallowed whole. They cannot be dissolved in water.

    When your Rescriptor supply starts to run low, get more from your doctor or pharmacy. It is important that you do not run out of Rescriptor. If you stop the medicine for even a short time, the amount of HIV in your body can increase or it can become resistant to the effects of Rescriptor.

    If you take antacids, you should take them at least 1 hour before or 1 hour after you take Rescriptor because they can slow the absorption of Rescriptor. Also, take Rescriptor with acidic beverages (such as orange juice or cranberry juice) if you do not secrete enough acid in your stomach.

  • What should I avoid while taking Rescriptor?

    Do not breastfeed while you are taking Rescriptor.

    Do not have unprotected sex and do not share needles.

  • What are possible food and drug interactions associated with Rescriptor?

    If Rescriptor is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Rescriptor may interact with numerous medications. Therefore, it is very important that you tell your doctor about any other medications you are taking.

  • What are the possible side effects of Rescriptor?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: diarrhea, headache, nausea, rash, tiredness

  • Can I receive Rescriptor if I am pregnant or breastfeeding?

    The effects of Rescriptor during pregnancy and breastfeeding are unknown. It is recommended that you do not breastfeed your baby if you are infected with HIV. This is because your baby could become infected with HIV through your breast milk. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Rescriptor?

    If you miss a dose of Rescriptor, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once. If you forget a lot of doses, talk to your doctor about how you should continue taking your medicine.

  • How should I store Rescriptor?

    Store at room temperature and away from heat and moisture.