Aggrenox

Generic name: Aspirin and extended-release dipyridamole

What is Aggrenox?

Aggrenox is used to reduce the chances of a stroke in people who have had a "mini-stroke" (transient ischemic attack) or a full-scale stroke due to a blood clot blocking an artery in the brain.

What is the most important information I should know about Aggrenox?

Because of the aspirin in Aggrenox, this product cannot be used by people who have an allergy to aspirin and other nonsteroidal anti-inflammatory drugs such as Advil, Motrin, and Naprosyn, or by people who suffer asthma attacks after taking aspirin.

Who should not take Aggrenox?

Do not take Aggrenox if you are allergic to any of its ingredients, have asthma, a persistent runny nose, or nasal polyps, or if you have severe liver or kidney disease. Also, because this drug contains aspirin, it is not recommended for children and teenagers, as it may cause a dangerous brain disorder called Reye's syndrome.

What should I tell my doctor before I take the first dose of Aggrenox?

Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Aggrenox. Also, talk to your doctor about your complete medical history, especially if you have an ulcer, stomach problems, bleeding disorders, or will be having surgery or dental work while taking this medication.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The recommended dosage is one capsule twice a day, in the morning and evening.

How should I take Aggrenox?

Aggrenox should be taken once in the morning and once in the evening. The capsule should be swallowed whole without chewing. This drug may be taken with or without food.

What are possible food and drug interactions associated with Aggrenox?

If Aggrenox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aggrenox with heart and blood pressure medications, acetazolamide, blood pressure medications classified as beta-blockers, blood-thinning drugs, gout medications, methotrexate, nonsteroidal anti-inflammatory drugs, oral diabetes drugs, seizure medications, and diuretics.

If you suffer from the muscle disease myasthenia gravis, treatment with Aggrenox may interfere with your drug therapy.

What are the possible side effects of Aggrenox?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: abdominal pain, back pain, bleeding, diarrhea, dizziness, fatigue, headache, indigestion, joint pain, nausea, pain, vomiting

Can I receive Aggrenox if I am pregnant or breastfeeding?

Do not take Aggrenox if you are pregnant, plan to become pregnant, or breastfeeding. The aspirin in this drug may cause low birth weight, brain hemorrhages in premature births, stillbirths and neonatal death.

What should I do if I miss a dose of Aggrenox?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

How should I store Aggrenox?

Store at room temperature.