Drugs and Supplements

Prescription Drugs

Arimidex, Anastrozole, side effects, drug interactions, overdose, dosage

Arimidex

Generic name: Anastrozole


What is Arimidex?

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Arimidex is a first-line treatment of breast cancer in postmenopausal women. Arimidex is also used to treat advanced breast cancer in postmenopausal women whose disease has spread to other parts of the body following treatment with tamoxifen, another anticancer drug. Arimidex can also be prescribed along with other drugs to treat the early stages of breast cancer in postmenopausal women.


What is the most important information I should know about Arimidex?

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Arimidex may increase the risk of cardiovascular events in patients with pre-existing ischemic heart disease. It may also cause a reduction in bone mineral density or raise blood cholesterol levels.


Who should not take Arimidex?

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Do not take Arimidex if you are pregnant or if you have an allergicreaction to the drug.


What should I tell my doctor before I take the first dose of Arimidex?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Arimidex. Also, talk to your doctor about your complete medical history, especially if you have ever had heart problems, high cholesterol, or osteoporosis.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual dose is a 1-milligram tablet taken once a day. If Arimidex is being used as an initial treatment for advanced breast cancer, you will continue taking the medication until it no longer works against the tumor. The optimal duration of therapy for early breast cancer has not been determined.


How should I take Arimidex?

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Take Arimidex exactly as directed.


What should I avoid while taking Arimidex?

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Avoid becoming pregnant or nursing a baby while taking this drug.


What are possible food and drug interactions associated with Arimidex?

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Certain drugs may decrease the effectiveness of Arimidex, including tamoxifen and estrogen-containing drugs. Be sure to tell your doctor about any medication you are taking.


What are the possible side effects of Arimidex?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: coughing, diarrhea, dizziness, general aches and pains, headache, hot flashes, nausea, nerve pain, rash, shortness of breath, vomiting, water retention


Can I receive Arimidex if I am pregnant or breastfeeding?

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If you are pregnant or plan to become pregnant, do not take Arimidex. In animal studies, this medication has caused severe birth defects, including incomplete bone formation and low birth weight; it could be poisonous to your unborn child. Arimidex also increases your chances of having a miscarriage or a stillborn baby. If you should accidentally become pregnant, tell your doctor immediately.

It is not known whether Arimidex passes into breast milk. Because of the potential risk to the infant, breastfeeding while using this drug is not recommended. Consult your doctor before breastfeeding.


What should I do if I miss a dose of Arimidex?

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Take the forgotten dose if you remember within 12 hours. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.


How should I store Arimidex?

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Store at room temperature.