Avapro

Generic name: Irbesartan

What is Avapro?

Avapro is used to treat high blood pressure. A member of the new family of drugs called angiotensin II receptor antagonists, it works by preventing the hormone angiotensin II from narrowing the blood vessels, an action that tends to raise blood pressure. Avapro may be prescribed alone or with other blood pressure medications.

In people with type 2 diabetes and high blood pressure, Avapro is also prescribed to stave off damage to the kidneys, often delaying the need for dialysis and a kidney transplant.

What is the most important information I should know about Avapro?

You must take Avapro regularly for it to be effective. Since blood pressure declines gradually, it may be a couple of weeks before you get the full benefit of Avapro, and you must continue taking it even if you are feeling well. Avapro does not cure high blood pressure, it merely keeps it under control.

Who should not take Avapro?

Do not begin treatment with Avapro if you are allergic to any of its ingredients.

What should I tell my doctor before I take the first dose of Avapro?

Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Avapro. Also, talk to your doctor about your complete medical history, especially if you have kidney disease.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

High Blood Pressure

Adults: The recommended starting dose of Avapro is 150 milligrams (mg) once a day. If your blood pressure remains elevated, your dose will be gradually increased to 300 mg once a day.

If you are being treated with hemodialysis or high doses of diuretics, you'll be started at a lower dose of 75 mg once a day.

Kidney Damage from Type 2 Diabetes

The usual dose is 300 mg once a day.

Children: For children 6 to 12 years old, the typical starting dose is 75 mg once a day. If blood pressure is still too high, the dose may be increased to 150 mg once a day. Children 13 to 16 years old are usually given the adult dosage.

How should I take Avapro?

Take your dose of Avapro around the same time every day, with or without food.

What are possible food and drug interactions associated with Avapro?

If Avapro is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Avapro with tolbutamide.

What are the possible side effects of Avapro?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: diarrhea, fatigue, heartburn, respiratory tract infection

Can I receive Avapro if I am pregnant or breastfeeding?

Avapro can cause injury or even death to the unborn child when used during the last 6 months of pregnancy. As soon as you learn you're pregnant, stop taking Avapro and call your doctor.

It is not known whether Avapro appears in breast milk, but because of potential risks to the newborn, it's considered best to avoid using the drug while breastfeeding. You and your doctor should decide whether to give up nursing or discontinue Avapro.

What should I do if I miss a dose of Avapro?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

How should I store Avapro?

Store at room temperature.