Avalide

Generic name: Irbesartan and hydrochlorothiazide

What is Avalide?

Avalide is a combination medication used to treat high blood pressure. One component, irbesartan, belongs to a class of blood pressure medications that prevents the hormone angiotensin II from constricting the blood vessels, thereby allowing blood to flow more freely and keeping blood pressure down. The other component, hydrochlorothiazide, is a diuretic that increases the output of urine, removing excess fluid from the body and thus lowering blood pressure.

What is the most important information I should know about Avalide?

When used in the second and third trimesters of pregnancy, Avalide can cause injury and even death to the unborn child. Stop taking Avalide as soon as you know you are pregnant. If you know you are pregnant or plan to become pregnant, tell your doctor immediately.

Who should not take Avalide?

If Avalide gives you an allergic reaction, you'll be unable to use it. You should also avoid it if you have an allergy to sulfa drugs, and if you're unable to urinate.

What should I tell my doctor before I take the first dose of Avalide?

Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Avalide. Also, talk to your doctor about your complete medical history, especially if you have liver or kidney disease, diabetes, gout, or lupus erythematosus.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual starting dose of Avalide is 1 lower-strength tablet daily.

It will take 2 to 4 weeks for Avalide to reach its maximum effectiveness. If your blood pressure does not respond to the initial dosage, your doctor may increase the dosage to 1 higher-strength tablet or 2 lower-strength tablets taken once a day.

How should I take Avalide?

Avalide can be taken with or without food.

What should I avoid while taking Avalide?

Avoid becoming dedhydrated while taking Avalide. Inadequate fluid intake or loss of fluids may result in low blood pressure, leading to lightheadedness or fainting. Seek medical attention if symptoms of hypersensitivity reactions, electrolyte imbalance (dry mouth, thirst, weakness, lethargy), lightheadedness, or fainting occur.

What are possible food and drug interactions associated with Avalide?

If Avalide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Avalide with the following: alcohol; adrenocorticotropic hormone (ACTH); barbiturates such as phenobarbital and secobarbital; cholestyramine; colestipol; insulin; lithium; narcotic painkillers such as acetaminophen, codeine phosphate, meperidine hydrochloride, and oxycodone hydrochloride; nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen sodium; other blood pressure medications such as atenolol and nifedipine; oral diabetes drugs such as chlorpropamide, glipizide, and glyburide; and steroids such as prednisone.

What are the possible side effects of Avalide?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: dizziness, fatigue, influenza, muscle and bone pain, nausea, swelling due to water retention, vomiting

Can I receive Avalide if I am pregnant or breastfeeding?

When used in the second and third trimesters of pregnancy, Avalide can cause injury and even death to the unborn child. Stop taking Avalide as soon as you know you are pregnant. If you know you are pregnant or plan to become pregnant, tell your doctor immediately.

Avalide appears in breast milk and can affect the nursing infant. If this medication is essential to your health, your doctor may advise you to stop breastfeeding while you are taking Avalide.

What should I do if I miss a dose of Avalide?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

How should I store Avalide?

Store at room temperature.