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Drugs and Supplements

Prescription Drugs

Cardizem/Cardizem CD/Cardizem LA/Cardizem SR, Diltiazem hydrochloride, side effects, drug interactions, overdose, dosage

Cardizem/Cardizem CD/Cardizem LA/Cardizem SR

Generic name: Diltiazem hydrochloride


What is Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Cardizem and Cardizem CD (a controlled release form of diltiazem) are used to treat chest pain usually caused by lack of oxygen to the heart due to clogged arteries (angina). Cardizem and Cardizem LA (an extended release, once-a-day tablet form of diltiazem) are used to treat angina caused by exertion. Cardizem CD and Cardizem LA are also used to treat high blood pressure. Cardizem SR is used only for the treatment of high blood pressure.


What is the most important information I should know about Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Cardizem does not cure high blood pressure; it only controls it. You must continue to take Cardizem regularly.

If you are taking Cardizem for chest pain, do not stop suddenly. This can lead to an increase in your attacks.


Who should not take Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Do not take Cardizem if you have sick sinus syndrome or types of irregular heartbeat known as second- or third-degree heart block, unless you have a ventricular pacemaker. Avoid Cardizem if you've just suffered a heart attack or have lung congestion.

Do not take Cardizem if you have low blood pressure or if you are allergic to the drug.


What should I tell my doctor before I take the first dose of Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Cardizem. Also, talk to your doctor about your complete medical history, especially if you have chronic heart failure, kidney disease, or liver disease.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Cardizem

Adults: The average daily dose is 180 milligrams (mg) to 360 mg, divided into 3 or 4 smaller doses.

Cardizem CD

Adults: This is a once-a-day form of Cardizem. For high blood pressure, starting doses range from 180-240 mg. For chest pain, doses range from 120-180 mg.

Cardizem LA

Adults: This is a once-a-day form of Cardizem. For high blood pressure, when used alone, doses start at 180-240 mg and may be increased to as much as 540 mg once daily. For chest pain, the starting dose is 180 mg once daily with increases every 7-14 days if needed.

Cardizem SR

Adults: The initial dosage is 60-120 mg taken 2 times a day. The usual dose is 240-360 mg a day.


How should I take Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Take Cardizem before meals and at bedtime. Cardizem CD, Cardizem LA, and Cardizem SR should be swallowed whole.

Take Cardizem exactly as prescribed by your doctor, even if you do not have any symptoms.


What are possible food and drug interactions associated with Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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If Cardizem is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Cardizem with the following: beta-blockers, such as atenolol or propranolol; carbamazepine; cimetidine; cyclosporine; digoxin; lovastatin; midazolam; rifampin; and triazolam.


What are the possible side effects of Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: abnormally slow heartbeat, dizziness, fatigue, fluid retention, flushing, headache, nausea, rash, weakness


Can I receive Cardizem/Cardizem CD/Cardizem LA/Cardizem SR if I am pregnant or breastfeeding?

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The effects of Cardizem during pregnancy and breastfeeding are unknown. Tell you doctor immediately if you are pregnant, plan to become pregnant, or you are breastfeeding.


What should I do if I miss a dose of Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Never take 2 doses at the same time.


How should I store Cardizem/Cardizem CD/Cardizem LA/Cardizem SR?

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Store at room temperature away from moisture.