Demadex

Generic name: Torsemide

What is Demadex?

Demadex is a diuretic (water pill) prescribed to reduce the water retention and swelling that often accompany congestive heart failure, kidney disease, and liver disease. It is also prescribed for high blood pressure, either alone or with other medications.

What is the most important information I should know about Demadex?

Demadex has been known to cause dehydration, chemical imbalances in the body, and a reduction in the volume of blood. Symptoms of these problems include dryness of the mouth, thirst, weakness, drowsiness, restlessness, muscle pain or fatigue, low blood pressure, diminished urination, rapid heartbeat, nausea, and vomiting. If any of these symptoms develop, discontinue Demadex and contact your doctor immediately.

Who should not take Demadex?

You should avoid Demadex if you have had a previous allergic reaction to the drug or to sulfonylurea drugs, which include certain diabetes medications. Do not take Demadex if you are unable to urinate.

What should I tell my doctor before I take the first dose of Demadex?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Demadex. Also, talk to your doctor about your complete medical history, especially if you have liver problems, high cholesterol, diabetes, hearing problems, or if you have allergies to sulfur or sulfur medications.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Congestive Heart Failure

Adults: The usual initial dose is 10 milligrams (mg) or 20 mg once a day. If this proves inadequate, your doctor may approximately double the dose until the desired response is obtained.

Chronic Kidney Failure

Adults: The usual initial dose is 20 mg once a day. If this proves inadequate, your doctor may approximately double the dose until the desired response is obtained.

Cirrhosis of the Liver

Adults: The usual initial dose is 5 or 10 mg once a day, administered along with other medications called "aldosterone antagonists" or "potassium-sparing diuretics." If this proves inadequate, your doctor will approximately double the dose until the desired response is obtained.

High Blood Pressure

Adults: The usual initial dose is 5 mgonce a day. If, after 4 to 6 weeks your blood pressure is still too high, your doctor may increase the dose to 10 mg once a day. If that isn't sufficient, your doctor may add another drug to your treatment plan.

Safety and effectiveness in children have not been established.

How should I take Demadex?

Take this medication exactly as prescribed with or without food.

What are possible food and drug interactions associated with Demadex?

If Demadex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Demadex with the following: aminoglycoside antibiotics, aspirin and other nonsteroidal anti-inflammatory drugs, cholestyramine, ethacrynic acid, lithium, probenecid

What are the possible side effects of Demadex?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: headache, excessive urination, dizziness, runny nose, weakness, diarrhea, increased cough, constipation, nausea, joint pain, difficult digestion, sore throat, muscle pain, chest pain, insomnia, edema, nervousness

Can I receive Demadex if I am pregnant or breastfeeding?

The effects of Demadex during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Demadex should be used during pregnancy only if clearly needed. It is not known whether Demadex is excreted in breast milk. Consult your doctor before taking Demadex if you are breastfeeding or planning to breastfeed.

What should I do if I miss a dose of Demadex?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

How should I store Demadex?

Store Demadex at room temperature. Do not freeze.