Drugs and Supplements

Prescription Drugs

Differin, Adapalene, side effects, drug interactions, overdose, dosage

Differin

Generic name: Adapalene


What is Differin?

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Differin is prescribed for the treatment of acne.


What is the most important information I should know about Differin?

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Differin makes your skin more sensitive to sunlight. While using this product, keep your exposure to the sun at a minimum, and protect yourself with sunscreen and clothing. Never apply Differin to sunburned skin.


Who should not take Differin?

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Do not use Differin if you are sensitive to adapalene or any other components of the gel.


What should I tell my doctor before I take the first dose of Differin?

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Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you have eczema or sunburned skin.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults and Children 12 years and older: The usual dose is a thin film applied over the acne-affected area just before bedtime.


How should I take Differin?

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Differin should be applied once a day at bedtime. Wash the affected areas, then apply a thin layer of the gel. Avoid eyes, lips, mouth, and nostrils. If you are using a single-use pledget, remove it from the foil just before using, and discard it after applying the medication. Do not use if the seal is broken.

Use Differin exactly as prescribed. Applying excessive amounts or using the gel more than once a day will not produce better results and may cause severe redness, peeling, and discomfort. If you have an allergic reaction or severe irritation, stop using the medication and call your doctor.

In the first few weeks of treatment, your acne may actually seem to get worse. This just means the medication is working on hidden acne sores. Continue using the product. It can take as much as 8 to 12 weeks before you start to see improvement in your condition.


What should I avoid while taking Differin?

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Remember that Differin increases sensitivity to sunlight. Take measures to protect yourself from overexposure. Wind and cold weather may also be irritating. Do not apply Differin to cuts, abrasions, eczema, or sunburned skin.


What are possible food and drug interactions associated with Differin?

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Avoid using Differin with any other product that can irritate the skin, such as medicated soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices, and lime.

Special caution is necessary if you have used, or are currently using, any skin product containing sulfur, resorcinol, or salicylic acid. Do not use such a product with Differin. If you have used one of these products recently, do not begin Differin treatment until the effects of the other product have subsided.


What are the possible side effects of Differin?

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Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Differin.

Side effects are most likely to occur during the first 2 to 4 weeks and usually diminish with continued treatment. If side effects are severe, your doctor may advise you to reduce the frequency of use or discontinue the drug entirely. Side effects disappear when the drug is stopped.

Side effects may include: Acne flare-ups, burning, dryness, irritation, itching, redness, scaling, stinging, sunburn


Can I receive Differin if I am pregnant or breastfeeding?

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The effects of Differin during pregnancy and breastfeeding have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately. It is not known whether Differin appears in breast milk. Consult your doctor if you plan on breastfeeding.


What should I do if I miss a dose of Differin?

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If you miss a dose of this drug, skip it. Do not take an extra dose to make up for missed doses.


How should I store Differin?

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Store at room temperature.