Inderide

Generic name: Propranolol hydrochloride and hydrochlorothiazide

What is Inderide?

Inderide is used to treat high blood pressure. It combines a beta-blocker with a diuretic (water pill). Beta-blockers decrease the force and rate of heart contractions, thus lowering blood pressure. Diuretics help your body produce and eliminate more urine, which also helps lower blood pressure.

What is the most important information I should know about Inderide?

Do not suddenly stop taking Inderide without speaking to your doctor. Worsening of chest pain, and in some cases, heart attacks, have been reported. If you are stopping Inderide, gradually reduce the dose over at least a few weeks.

If you have high blood pressure, you must take Inderide regularly to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Inderide. You must continue taking it even if you are feeling well. Inderide does not cure high blood pressure; it only keeps it under control.

Who should not take Inderide?

Do not use Inderide if you are sensitive to any component of the drug or to sulfa drugs. Also, do not use Inderide if you have any of the following conditions: asthma, certain types of irregular heartbeat, chronic heart failure, inadequate blood supply to the circulatory system (cardiogenic shock), difficulty urinating, slow heartbeat

What should I tell my doctor before I take the first dose of Inderide?

Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Inderide. Also, talk to your doctor about your complete medical history, especially if you have asthma, certain types of irregular heartbeat, chronic heart failure, diabetes, glaucoma (excessive pressure in the eyes), an overactive thyroid, kidney or liver disease, tumors of the adrenal gland, upcoming major surgery

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual dose is 1 Inderide tablet taken twice a day. Your doctor will tailor your dosage according to your response to the main ingredient in Inderide. Your doctor may use Inderide in combination with other high blood pressure drugs to achieve the desired effect.

This drug is also available in a sustained-release formulation, called Inderide LA, for once-a-day dosing.

The safety and effectiveness of Inderide in children have not been established.

How should I take Inderide?

Take Inderide exactly as directed by your doctor. Do not stop taking Inderide without first talking to your doctor. Inderide can be taken with or without food. Take Inderide at the same time every day.

What should I avoid while taking Inderide?

Avoid driving, operating machinery, or performing other activities that require your complete attention until you know how this medication affects you. Inderide may cause drowsiness, dizziness, and blood pressure changes.

What are possible food and drug interactions associated with Inderide?

If Inderide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Inderide with the following: adrenocorticotropic hormone, alcohol, aluminum hydroxide gel, antipyrine, calcium-blocking drugs such as verapamil, chlorpromazine, cimetidine, corticosteroids such as prednisone, haloperidol, insulin, lidocaine, NSAIDs such as ibuprofen or naproxen, norepinephrine, phenobarbital, phenytoin, reserpine, rifampin, theophylline, thyroxine, and tubocurarine.

What are the possible side effects of Inderide?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: allergic reactions, blood disorders, chronic heart failure, depression, inflammation of the pancreas, light-headedness, low blood pressure, nausea, slow heartbeat, vomiting

Can I receive Inderide if I am pregnant or breastfeeding?

The effects of Inderide during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding. Do not breastfeed while taking Inderide.

What should I do if I miss a dose of Inderide?

Take it as soon as you remember. If the next dose is within 6 hours, skip the missed dose and go back to your regular schedule. Do not take 2 doses at the same time.

How should I store Inderide?

Store at room temperature in a tightly closed container, protected from moisture, freezing, and excessive heat.