Isordil

Generic name: Isosorbide dinitrate

What is Isordil?

Isordil is prescribed to prevent angina pectoris (suffocating chest pain), which occurs when the heart arteries become constricted and sufficient oxygen does not reach the heart tissues. Isordil dilates the blood vessels by relaxing the muscles in their walls. Oxygen flow improves as the vessels relax, and chest pain is prevented.

What is the most important information I should know about Isordil?

Isordil may cause severe low blood pressure (possibly marked by dizziness or fainting), especially when you stand or sit up quickly. Alcohol may worsen this condition. People taking diuretics (water pills) or those who have low blood pressure should use Isordil with caution.

Who should not take Isordil?

Do not take Isordil if you are allergic to any of its ingredients, or to other nitrates or nitrites.

What should I tell my doctor before I take the first dose of Isordil?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Isordil. Also, talk to your doctor about your complete medical history, especially if you have anemia, glaucoma, a previous head injury or heart attack, heart disease, low blood pressure, or thyroid disease.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual starting dose of Isordil is 5 milligrams (mg) to 20 mg, 2 or 3 times daily. For maintenance therapy, between 10 mg to 40 mg, 2 or 3 times daily is recommended.

How should I take Isordil?

Take exactly as prescribed by your doctor.

What should I avoid while taking Isordil?

Avoid abruptly stopping this medication because it could result in additional chest pain. You should follow your doctor's plan for a gradual withdrawal schedule.

What are possible food and drug interactions associated with Isordil?

If Isordil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Isordil with the following: alcohol, dilitiazem hydrochloride, nifedipine, and sildenafil citrate (Viagra).

What are the possible side effects of Isordil?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: dizziness, headache, lightheadedness, low blood pressure, weakness

Can I receive Isordil if I am pregnant or breastfeeding?

The effects of Isordil during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

What should I do if I miss a dose of Isordil?

Take it as soon as you remember. If the next dose is within 6 hours, skip the missed dose and go back to your regular schedule. Do not take 2 doses at the same time.

How should I store Isordil?

Store at room temperature, in a tightly closed container. Protect from light and excessive heat.