Drugs and Supplements

Prescription Drugs

Librax, Chlordiazepoxide hydrochloride and clidinium bromide, side effects, drug interactions, overdose, dosage

Librax

Generic name: Chlordiazepoxide hydrochloride and clidinium bromide


What is Librax?

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Librax is used with other medications for the treatment of peptic ulcers, irritable bowel syndrome (spastic colon), and acute enterocolitis (inflammation of the colon and small intestine). It combines a benzodiazepine—chlordiazepoxide--and clidinium, which is an antispasmodic medication.


What is the most important information I should know about Librax?

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Because of its sedative effects, you should not operate heavy machinery, drive, or engage in other hazardous tasks that require you to be mentally alert while you are taking Librax.


Who should not take Librax?

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Do not take Librax if you have glaucoma (elevated pressure in the eye), an enlarged prostate, or a bladder obstruction. If you are sensitive to or have ever had an allergic reaction to any component of this drug, you should not take Librax.


What should I tell my doctor before I take the first dose of Librax?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Librax. Also, talk to your doctor about your complete medical history, especially if you have glaucoma, difficulty urinating or a bladder obstruction, or an enlarged prostate.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual dose is 1 to 2 capsules, 3 to 4 times a day before meals and at bedtime.


How should I take Librax?

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Take Librax before meals and at bedtime. Librax can make your mouth dry. For temporary relief, suck a hard candy or chew gum.


What should I avoid while taking Librax?

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Avoid drinking alcohol while taking Librax; as it may increase its drowsiness and dizziness side effects.

Because of its sedative effects, you should not operate heavy machinery, drive, or engage in other hazardous tasks that require you to be mentally alert while you are taking Librax.

Librax can be habit-forming and has been associated with drug dependence and addiction. Be very careful taking Librax if you have ever had problems with alcohol or drug abuse. Never take more than the prescribed amount.

In addition, you should not stop taking Librax suddenly, because of the risk of withdrawal symptoms (convulsions, cramps, tremors, vomiting, sweating, depression, and sleeplessness). If you have been taking Librax over a long period of time, your doctor will decrease your dose gradually.

Avoid becoming overheated; Librax decreases sweating and therefore may increase the risk of heat stroke.


What are possible food and drug interactions associated with Librax?

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If Librax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Librax with any of the following: alcohol, antidepressants known as monoamine oxidase inhibitors MAOIs, such as phenelzine or tranylcypromine, belladonna, benzodiazepines such as alprazolam and diazepam, blood-thinners such as warfarin, diphenhydramine, ketoconazole, major tranquilizers such as chlorpromazine and trifluoperazine, potassium supplements


What are the possible side effects of Librax?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: blurred vision, changes in sex drive, confusion, constipation, drowsiness, dry mouth, fainting, lack of coordination, liver problems, minor menstrual irregularities, nausea, skin eruptions, swelling due to fluid retention, urinary difficulties, yellowing of skin and eyes


Can I receive Librax if I am pregnant or breastfeeding?

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Several studies have found an increased risk of birth defects if Librax is taken during the first 3 months of pregnancy. Therefore, Librax is rarely recommended for use by pregnant women. If you are pregnant, plan to become pregnant, or are breastfeeding, inform your doctor immediately.


What should I do if I miss a dose of Librax?

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Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.


How should I store Librax?

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Store away from heat, light, and moisture.