Drugs and Supplements

Prescription Drugs

Megace ES, Megestrol acetate, side effects, drug interactions, overdose, dosage

Megace ES

Generic name: Megestrol acetate


What is Megace ES?

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Megace ES is used for the treatment of anorexia (loss of appetite), cachexia (malnutrition), or unexplained, significant weight loss in patients with a diagnosis of AIDS.


What is the most important information I should know about Megace ES?

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Megace ES may cause severe problems during pregnancy. It is recommended that women of child-bearing age avoid becoming pregnant.


Who should not take Megace ES?

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This medication should not be taken if you have a history of being too sensitive to megestrol acetate or any component of the formulation. Do not take this medication if you are or think you may be pregnant.


What should I tell my doctor before I take the first dose of Megace ES?

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Mention any prescription, over-the-counter, or herbal medications you are taking before beginning treatment with Megace ES. Also, talk to your doctor about your complete medical history, especially if you are pregnant, planning to become pregnant, or are nursing.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change your dosage or stop taking your medication without your doctor's approval.

Adults: The recommended initial dosage of Megace ES oral suspension is 625 mg/day (5 mL or one teaspoon daily).


How should I take Megace ES?

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Shake contents of the bottle well before pouring into a teaspoon/measuring spoon and swallowing.


What should I avoid while taking Megace ES?

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Pregnancy should be avoided while taking this medication.


What are possible food and drug interactions associated with Megace ES?

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If Megace ES is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining with rifabutin or zidovudine.


What are the possible side effects of Megace ES?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: decreased sex drive, diarrhea, fever, gas, headache, increased blood pressure, impotence, nausea, rash, sleeplessness, upset stomach, vomiting


Can I receive Megace ES if I am pregnant or breastfeeding?

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Do not begin therapy with Megace ES if you are pregnant, planning to become pregnant, or are breastfeeding. This drug may cause severe problems during pregnancy. Megace ES may pass into breast milk.


What should I do if I miss a dose of Megace ES?

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Take your dose of Megace ES as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not double up on doses.


How should I store Megace ES?

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Store at room temperature.