Drugs and Supplements

Prescription Drugs

Benzoyl peroxide, side effects, drug interactions, overdose, dosage

Benzoyl peroxide


What is Benzoyl peroxide?

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Benzoyl peroxide is a topical medication used to treat acne. It can be used alone or with other treatments, including antibiotics and products that contain retinoic acid, sulfur, or salicylic acid.


What is the most important information I should know about Benzoyl peroxide?

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Benzoyl peroxide is for external use only. Avoid contact with your eyes, nose, lips, or throat. If the drug does touch these areas accidentally, rinse with water. If your skin becomes severely irritated, stop using the drug and call your doctor.


Who should not take Benzoyl peroxide?

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Do not use this drug if you are sensitive to or allergic to benzoyl peroxide or any other components of the drug.


What should I tell my doctor before I take the first dose of Benzoyl peroxide?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you are sensitive to medications derived from benzoic acid (including certain topical anesthetics).


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults and children ≥12 years: Gently rub the medication into all affected areas once or twice a day. If you are fair-skinned or live in an excessively dry climate, you should probably start with one application a day. A visible difference may be noticed in 3 weeks, and the maximum change is usually seen in 8 to 12 weeks. You can continue to use benzoyl peroxide for as long as your doctor thinks it is necessary.


How should I take Benzoyl peroxide?

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Cleanse the affected area thoroughly before applying the medication. Benzoyl peroxide should then be gently rubbed in.


What should I avoid while taking Benzoyl peroxide?

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Avoid getting the medication on your hair or clothes, since it could bleach or discolor them. Also, stay out of the sun as much as possible and use a sunscreen.


What are possible food and drug interactions associated with Benzoyl peroxide?

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When used with sunscreens containing PABA (para-aminobenzoic acid), benzoyl peroxide may cause temporary skin discoloration.


What are the possible side effects of Benzoyl peroxide?

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Side effects cannot be anticipated. If any develop or change in intensity, notify your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue using this drug.

Side effects may include: allergic reaction (itching, rash in area where the medication was applied), excessive drying (red and peeling skin and possible swelling)


Can I receive Benzoyl peroxide if I am pregnant or breastfeeding?

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The effects of benzoyl peroxide during pregnancy have not been adequately studied. It should be used only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately. This medication may appear in breast milk and could affect a nursing infant. Consult your doctor before breastfeeding.


What should I do if I miss a dose of Benzoyl peroxide?

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If you miss an application of this drug, skip it. Do not apply it more often than your doctor instructs.


How should I store Benzoyl peroxide?

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Store at room temperature.