Entereg

Generic name: Alvimopan

What is Entereg?

Entereg is used to accelerate the time to upper and lower gastrointestinal recovery following partial large or small bowel resection surgery with primary anastomosis.

What is the most important information I should know about Entereg?

Entereg is only used in a hospital setting and for no more than 7 days after bowel resection surgery.

Who should not take Entereg?

Do not take Entereg if you have taken any opioid medication for more than 7 consecutive days immediately prior to taking Entereg. Do not take Entereg if you have any kidney or liver problems. Safety has not been established in children.

What should I tell my doctor before I take the first dose of Entereg?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Entereg. Also, talk to your doctor about your complete medical history, especially if you have a history of kidney or liver problems, or are pregnant or breastfeeding. Tell your doctor if you have taken any opioid medication for more than 7 consecutive days immediately prior to taking Entereg.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The typical dose is 12 milligrams (mg) given 30 minutes to 5 hours prior to surgery, followed by 12 mg twice daily for up to 7 days for a maximum of 15 doses.

How should I take Entereg?

Take Entereg before eating, as prescribed by your doctor.

What should I avoid while taking Entereg?

Avoid the use of any opioid medications before or during treatment with Entereg.

What are possible food and drug interactions associated with Entereg?

If Entereg is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Entereg with high-fat meals or opioids.

What are the possible side effects of Entereg?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: anemia, constipation, dyspepsia, flatulence, low potassium levels, back pain, urinary retention

Can I receive Entereg if I am pregnant or breastfeeding?

Avoid Entereg during pregnancy and breastfeeding. Talk with your doctor before taking this drug if you are pregnant, plan to become pregnant, or are breastfeeding.

What should I do if I miss a dose of Entereg?

Entereg is only administered in a hospital setting.

How should I store Entereg?

Entereg is only administered in a hospital setting.