Drugs and Supplements

Prescription Drugs

Eraxis, Anidulafungin, side effects, drug interactions, overdose, dosage

Eraxis

Generic name: Anidulafungin


What is Eraxis?

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Eraxis is used to treat fungal infections caused by Candida, including infections in the lining of the abdomen (intra-abdominal abscess and peritonitis) and throat infections.


What is the most important information I should know about Eraxis?

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Eraxis is not a self-administered antifungal. This drug is most likely given in a hospital setting, by a doctor or nurse.

Do not drive or perform other possibly unsafe tasks until you know how you react to Eraxis; this drug may cause dizziness or blurred vision. These effects may worsen if you take Eraxis with alcohol or certain medicines.

Eraxis only works against fungus; it does not treat viral infections (eg, the common cold).


Who should not take Eraxis?

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Do not take Eraxis if you are allergic to anidulafungin, any of its other ingredients, or if you have had sensitivity to other echinocandin antifungals (such as caspofungin) in the past.


What should I tell my doctor before I take the first dose of Eraxis?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking to avoid a possible interaction with Eraxis. Also, talk to your doctor about your complete medical history before beginning treatment with Eraxis. In addition, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: Candidemia and most Candida infections (abdominal)

Adults: The recommended dose for candidemia and most Candida infections is a single 200 milligram (mg) dose of Eraxis on day 1, followed by 100 mg daily dose thereafter. Duration of treatment should be based on the patient's clinical response. In general, treatment with Eraxis should continue for at least 14 days after the positive fungal test.

Esophageal (throat) candidiasis

Adults: The recommended dose for throat infections is a single 100 mg loading dose of Eraxis on Day 1, followed by 50 mg daily dose thereafter. Treatment should continue for a minimum of 14 days and for at least 7 days following the last symptom.


How should I take Eraxis?

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Eraxis will be administered by your doctor. To clear up your infection completely, use Eraxis for the full course of treatment. Keep using it even if you feel better in a few days.


What should I avoid while taking Eraxis?

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Do not drive or perform other possibly unsafe tasks until you know how you react to Eraxis; this drug may cause dizziness or blurred vision. These effects may become worse if you take it with alcohol or certain medicines.

Keep using Eraxis even if you feel better in a few days.

Eraxis will be administered by your doctor, keep your regular doctor appointments.


What are possible food and drug interactions associated with Eraxis?

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There have been no drug or food interactions which have been documented that interfere with Eraxis when given at the recommended dosing. However, it is important to discuss with your doctor all prescription and non-prescription medications and supplements that you are currently taking.


What are the possible side effects of Eraxis?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: diarrhea, headache, nausea, rash, upset stomach, vomiting, swelling, redness at the injection site, dark urine, fever, chills, or persistent sore throat, irregular heartbeat, leg redness, pale stools, shortness of breath, unusual bruising or bleeding, yellowing of the skin or eyes, or sever allergic reactions (rash, hives, itching, tightness in the chest, swelling of the face, lips, or tongue)


Can I receive Eraxis if I am pregnant or breastfeeding?

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If you are pregnant, planning to become pregnant, or are nursing, talk to your doctor before taking Eraxis. The effects of Eraxis on pregnancy are unknown, and it may pass into breast milk.


What should I do if I miss a dose of Eraxis?

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If you miss a dose of Eraxis, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.


How should I store Eraxis?

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Eraxis is usually handled and stored by a healthcare provider.