Evista

Generic name: Raloxifene hydrochloride

What is Evista?

Evista is prescribed to treat and help prevent osteoporosis.

What is the most important information I should know about Evista?

Because of Evista's tendency to promote clots, you should not take it during long periods of immobilization such as recovery from surgery or prolonged bed rest, or for 72 hours beforehand. If you are scheduled for surgery, make sure the doctor is aware that you are taking Evista. For the same reason, if you are going on a trip where your movement will be restricted, make a point of periodically getting up and walking around.

Evista is not needed prior to menopause and shouldn't be taken until menopause has passed. It has not been studied in premenopausal women and its use is not recommended.

If you develop unusual uterine bleeding or breast problems while taking Evista, tell your doctor immediately.

Never combine Evista with estrogen hormones.

Who should not take Evista?

Evista is not for use by women who are—or could become—pregnant. You should also avoid this drug if you have a history of blood clot formation, including deep vein thrombosis (blood clot in the legs), pulmonary embolism (blood clot in the lungs), and retinal vein thrombosis (blood clot in the retina of the eye), since Evista increases the risk of clots. Avoid the drug, too, if it gives you an allergic reaction.

What should I tell my doctor before I take the first dose of Evista?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you have congestive heart failure, liver problems, cancer, or high triglycerides.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Postmenopausal women: The recommended dosage is one 60-milligram tablet once a day.

How should I take Evista?

Take Evista once daily, at any time, with or without food.

What should I avoid while taking Evista?

Due to the risk of blood clots, avoid prolonged bed rest or restricted movement.

What are possible food and drug interactions associated with Evista?

If Evista is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Evista with the following: cholestyramine, clofibrate, diazepam, diazoxide, ibuprofen, indomethacin, naproxen, and warfarin.

What are the possible side effects of Evista?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: abdominal pain, arthritis, breast pain, bronchitis, chest pain, depression, diarrhea, dizziness, fever, flu symptoms, gas, gynecological problems, headache, hot flashes, increased cough, indigestion, infection, insomnia, joint pain, leg cramps, muscle ache, nasal inflammation, nausea, rash, sinusitis, sore throat, stomach and intestinal problems, sweating, swelling, tendon soreness, uterine discharge, urinary tract infection, vomiting, weight gain

Can I receive Evista if I am pregnant or breastfeeding?

Evista can harm a developing baby. Do not use if you are or may become pregnant. Also avoid breastfeeding while taking Evista.

What should I do if I miss a dose of Evista?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take a double dose.

How should I store Evista?

Store at room temperature.