Drugs and Supplements

Prescription Drugs

Granisol, Granisetron, side effects, drug interactions, overdose, dosage

Granisol

Generic name: Granisetron


What is Granisol?

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Granisol is an oral solution used to treat nausea and vomiting associated with cancer chemotherapy and radiation.


What is the most important information I should know about Granisol?

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Granisol does not stimulate stomach or intestinal movements. It should not be used following certain abdominal procedures, as it may mask progressive ileus (slowing of the bowel) or gastrointestinal distension. Before taking Granisol, tell your doctor if you have recently had stomach or intestinal surgery. You may need a dose adjustment or special tests to safely take this medication.


Who should not take Granisol?

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Do not take Granisol if you have any known allergic reaction to the drug or any of its components.


What should I tell my doctor before I take the first dose of Granisol?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Granisol. Also talk to your doctor about your complete medical history, especially if you have recently had stomach or intestinal surgery.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The recommended dosage of Granisol is 2 milligrams (mg) once daily or 1 mg twice daily.


How should I take Granisol?

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If your doctor has prescribed the once-daily dosage, take 2 teaspoonfuls (equivalent to 2 mg) of Granisol oral solution up to 1 hour before chemotherapy. If your doctor has prescribed the twice-daily regimen, take 1 teaspoonful (equivalent to 1 mg) up to 1 hour before chemotherapy and again 12 hours after therapy.


What should I avoid while taking Granisol?

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Do not use Granisol continuously except on the days of chemotherapy.


What are possible food and drug interactions associated with Granisol?

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If Granisol is taken with certain drugs, the effects of either could be increased, decreased, or altered. Always check with your doctor before combining Granisol with other medication.


What are the possible side effects of Granisol?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: headache, constipation, diarrhea, heartburn, allergic reactions

Signs of severe allergic reactions may include hives, difficulty breathing, and swelling of the throat. If any of these occur, seek immediate medical attention.


Can I receive Granisol if I am pregnant or breastfeeding?

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Granisol should not be used during pregnancy or breastfeeding.


What should I do if I miss a dose of Granisol?

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Ask your doctor what to do if you miss a dose.


How should I store Granisol?

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Store at room temperature.