Drugs and Supplements

Prescription Drugs

Hyalgan, Sodium hyaluronate, side effects, drug interactions, overdose, dosage

Hyalgan

Generic name: Sodium hyaluronate


What is Hyalgan?

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Hyalgan is used to relieve knee pain due to osteoarthritis. It is a sterile mixture that is made of highly purified sodium hyaluronate that comes from rooster combs.


What is the most important information I should know about Hyalgan?

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Hyalgan must be administered by a doctor. It is given in a shot directly into your knee joint.


Who should not take Hyalgan?

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You should not take this product if you had any previous allergic reaction to Hyalgan or similar materials (such as other hyaluronate products). You should not have an injection into the knee if you have infections or skin diseases around the injection site.


What should I tell my doctor before I take the first dose of Hyalgan?

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Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Hyalgan. Also tell your doctor about your complete medical history.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The recommended dosage is 20 milligrams per 2 milliliters, generally give once a week for a total of 5 injections. Some people may experience benefits after 3 injections given at weekly intervals.


How should I take Hyalgan?

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Hyalgan is administered by a healthcare provider as an injection into the knee joint.


What should I avoid while taking Hyalgan?

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Do not use disinfectants containing quaternary ammonium salts for skin preparation before receiving an injection of Hyalgan.


What are possible food and drug interactions associated with Hyalgan?

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If Hyalgan is taken with certain drugs, the effects of either could be increased, decreased, or altered. Always check with your doctor before combining Hyalgan with other medications, especially quaternary ammonium salts used in skin preparations.


What are the possible side effects of Hyalgan?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: allergic reactions, fever, low blood pressure, fainting, injection site pain, itching, gastrointestinal problems

Signs of severe allergic reactions may include hives, difficulty breathing, and swelling of the throat. If any of these occur, seek immediate medical attention.


Can I receive Hyalgan if I am pregnant or breastfeeding?

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Hyalgan should be avoided during pregnancy and breastfeeding.


What should I do if I miss a dose of Hyalgan?

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Ask your doctor for advice.


How should I store Hyalgan?

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Hyalgan should be stored at room temperature or cooler; it should not be frozen.