Ketorolac tromethamine

What is Ketorolac tromethamine?

Ketorolac, a nonsteroidal anti-inflammatory drug, is used to relieve moderately severe, acute pain. It is prescribed for a limited amount of time (no more than 5 days for adults and as a single dose for children), not for long-term therapy.

What is the most important information I should know about Ketorolac tromethamine?

Ketorolac can cause serious side effects, including ulcers and internal bleeding. Never take it for more than 5 days.

This drug should be used with caution if you have kidney or liver disease. It may cause liver inflammation or kidney problems in some people.

If you are an older adult or are taking blood thinners, use this drug cautiously.

Ketorolac is not recommended for long-term use, since side effects increase over time. This medication should be taken for no more than 5 days.

Who should not take Ketorolac tromethamine?

Do not take ketorolac if it has ever given you an allergic reaction. Also avoid this medication if you have ever had an allergic reaction—such as nasal polyps (tumors), swelling of the face, limbs, and throat, hives, wheezing, light-headedness—to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Do not take ketorolac if you have ever had a peptic ulcer or stomach or intestinal bleeding. Avoid it if you have severe kidney disease or bleeding problems.

Never combine this drug with aspirin, NSAIDs, or probenecid. Make sure your doctor is aware of any drug reactions you have experienced.

What should I tell my doctor before I take the first dose of Ketorolac tromethamine?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with ketorolac. Also talk to your doctor about your complete medical history, especially if you have ever had kidney or liver problems, ulcers, intestinal bleeding, heart disease, high blood pressure, or if you are taking blood thinners.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: Your doctor may give you ketorolac intravenously or intramuscularly to start, then have you switch to the tablets. Most patients take 2 tablets for the first dose (20 milligrams) and then 1 tablet (10 milligrams) every 4 to 6 hours. You should not take more than 40 milligrams per day and should not take ketorolac for more than 5 days in all.

Children: For children under 16, the doctor may prescribe a single dose of ketorolac, by intravenous or intramuscular injection, after an operation. Ketorolac is not recommended for children under 2 years.

How should I take Ketorolac tromethamine?

Take ketorolac exactly as prescribed. Take it with a full glass of water. Ketorolac works fastest when taken on an empty stomach, but an antacid can be taken if it causes upset.

What should I avoid while taking Ketorolac tromethamine?

Avoid lying down for about 20 minutes after taking ketorolac. This will help to prevent irritation of your upper digestive tract.

What are possible food and drug interactions associated with Ketorolac tromethamine?

If ketorolac is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining ketorolac with the following: blood pressure medication such as ACE inhibitors, antidepressants, antiepileptic drugs, aspirin and other NSAIDs, blood thinners such as warfarin, lithium, antianxiety medication, methotrexate, probenecid, alprazolam, and diuretics.

What are the possible side effects of Ketorolac tromethamine?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using ketorolac.

Side effects may include: diarrhea, dizziness, drowsiness, headache, indigestion, nausea, stomach and intestinal pain, swelling due to fluid retention

Can I receive Ketorolac tromethamine if I am pregnant or breastfeeding?

Ketorolac should not be taken late in pregnancy; during this period, it can harm the developing baby. If you are pregnant or plan to become pregnant, inform your doctor immediately. Ketorolac appears in breast milk and could affect a nursing infant. This medication should not be used while you are breastfeeding.

What should I do if I miss a dose of Ketorolac tromethamine?

If you take ketorolac on a regular schedule, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

How should I store Ketorolac tromethamine?

Store at room temperature, away from light.