Midrin

Generic name: Isometheptene mucate, dichloralphenazone, and acetaminophen

What is Midrin?

Midrin is prescribed for the treatment of tension headaches. It is also used to treat vascular headaches such as migraine.

What is the most important information I should know about Midrin?

Midrin can be used only after the headache starts. It does not prevent headaches.

Take Midrin cautiously if you have high blood pressure or any abnormal condition of the blood vessels outside of the heart, or have recently had a cardiovascular attack such as a heart attack or stroke.

Who should not take Midrin?

Unless directed to do so by your doctor, do not take Midrin if you have the eye condition called glaucoma or severe kidney disease, high blood pressure, a physical defect of the heart, or liver disease, or if you are currently taking antidepressant drugs known as MAO inhibitors, including phenelzine and tranylcypromine.

What should I tell my doctor before I take the first dose of Midrin?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with this drug. Also, talk to your doctor about your complete medical history, especially if you have heart disease, high blood pressure, or have ever had a stroke or heart attack.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Relief of Migraine Headache

Adults: The usual dosage is 2 capsules at once, followed by 1 capsule every hour until the headache is relieved; do not take more than 5 capsules within a 12-hour period.

Relief of Tension Headache

Adults: The usual dosage is 1 or 2 capsules every 4 hours up to a maximum of 8 capsules a day.

How should I take Midrin?

Take this medication exactly as prescribed by your doctor. You should start taking Midrin at the first sign of a migraine attack. Do not take more than the maximum dose of Midrin.

What should I avoid while taking Midrin?

Avoid alcoholic beverages.

What are possible food and drug interactions associated with Midrin?

If Midrin is taken with certain other drugs, the effects of either drug could be increased, decreased, or altered. It is especially important to check with your doctor before combining Midrin with the following: acetaminophen-containing pain relievers, antidepressants classified as MAO inhibitors including phenelzine and tranylcypromine, antihistamines such as diphenhydramine, and central nervous system depressants such as alprazolam, diazepam, and triazolam.

What are the possible side effects of Midrin?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: short periods of dizziness, skin rash

Can I receive Midrin if I am pregnant or breastfeeding?

If you are pregnant, plan to become pregnant, or are breastfeeding, check with your doctor before taking Midrin.

What should I do if I miss a dose of Midrin?

Take this medication only as needed.

How should I store Midrin?

Store at room temperature in a dry place.