Univasc

Generic name: Moexipril hydrochloride

What is Univasc?

Univasc is used in the treatment of high blood pressure. It is effective when used alone or with thiazide diuretics, which help rid the body of excess water.

What is the most important information I should know about Univasc?

Blood pressure medications known as angiotensin converting enzyme (ACE) inhibitors, such as Univasc, have been shown to cause injury and even death of the developing baby when used during the second and third trimesters of pregnancy. When pregnancy is confirmed, call your doctor right away Univasc.

Univasc can cause a severe drop in blood pressure if you lose too much liquid through excessive sweating, severe diarrhea, or vomiting. Contact your doctor immediately if you develop one of these problems.

You must take Univasc regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Univasc, and you must continue taking it even if you are feeling well. Univasc does not cure high blood pressure; it merely keeps it under control.

If you develop swelling of your face, around the lips, tongue, or throat; swelling of your arms and legs; sore throat; or difficulty breathing or swallowing, stop taking the drug and contact your doctor immediately. You may need emergency treatment.

Who should not take Univasc?

If you have ever had an allergic reaction to Univasc or other angiotensin converting enzyme (ACE) inhibitors such as captopril, enalapril, and lisinopril, you should not take Univasc.

What should I tell my doctor before I take the first dose of Univasc?

Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Univasc. Also, talk to your doctor about your complete medical history, especially if you have diabetes, liver disease, kidney disease, or if you are on dialysis. Make sure to also let your doctor know if you have a disease of connective tissue such as systemic lupus erythematosus, any type of heart disease, or if you have had a stroke.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: For people not taking a diuretic drug, the usual starting dose is 7.5 milligrams (mg) taken once a day, an hour before a meal. The dosage after that can range from 7.5 to 30 mg per day, taken in either a single dose or divided into 2 equal doses. The maximum dose is 60 mg per day. Your doctor will closely monitor the effect of Univasc and adjust it according to your individual needs.

People already taking a diuretic should stop taking it, if possible, 2 to 3 days before starting Univasc. This reduces the possibility of fainting or light-headedness. If the diuretic cannot be discontinued, the starting dosage of Univasc should be 3.75 mg. If Univasc alone does not control your blood pressure, your doctor will have you start taking a diuretic again.

For people with kidney problems, the usual starting dose is 3.75 mg a day. Your doctor may gradually raise the dose to a maximum of 15 mg a day.

Children: The safety and effectiveness of Univasc have not been established in children.

How should I take Univasc?

Univasc should be taken 1 hour before a meal. Try to get in the habit of taking your medication at the same time each day, such as 1 hour before breakfast, so that it is easier to remember. Always take Univasc exactly as prescribed.

What should I avoid while taking Univasc?

Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor first. In a medical emergency and before you have surgery, notify your doctor or dentist that you are taking Univasc.

Be careful if you are going to drive or do anything that requires you to be awake and alert while you are taking Univasc.

What are possible food and drug interactions associated with Univasc?

If Univasc is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Univasc with the following: diuretics (chlorothiazide, hydrochlorothiazide, furosemide), potassium supplements, potassium-sparing diuretics (spironolactone, amiloride hydrochloride/hydrochlorothiazide, hydrochlorothiazide/triamterene), or lithium.

What are the possible side effects of Univasc?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: cough, diarrhea, dizziness, fatigue, flu-like symptoms, flushing, infection of the tonsils, muscle pain, rash

Can I receive Univasc if I am pregnant or breastfeeding?

If you are pregnant, contact your doctor immediately for instructions on how to safely discontinue Univasc. If you plan to become pregnant, discuss the situation with your doctor as soon as possible.

The effects of Univasc during breastfeeding are unknown. If Univasc is essential to your health, your doctor may advise you to stop breastfeeding while you are taking the drug.

What should I do if I miss a dose of Univasc?

Take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and go back to your regular schedule. Do not double the dose.

How should I store Univasc?

Store at room temperature in a tightly closed container, away from moisture.