Uroxatral

Generic name: Alfuzosin hydrochloride

What is Uroxatral?

Uroxatral is used to treat the symptoms of an enlarged prostate—a condition technically known as benign prostatic hyperplasia or BPH. The walnut-sized prostate gland surrounds the urethra (the duct that drains the bladder). If the gland becomes enlarged, it can squeeze the urethra, interfering with the flow of urine. This can cause difficulty in starting urination, a weak flow of urine, and the need to urinate urgently or more frequently. Uroxatral doesn't shrink the prostate. Instead, it relaxes the muscle around it, freeing the flow of urine and decreasing urinary symptoms.

What is the most important information I should know about Uroxatral?

Benign enlargement of the prostate is not the only condition that can cause male urinary inefficiency and discomfort. Other possibilities include infection, obstruction, cancer of the prostate, and bladder disorders. Before prescribing Uroxatral, your doctor will want to do various tests to determine the cause of your urinary problems.

Stop taking Uroxatral immediately and call your doctor if symptoms of angina pectoris (chest pain due to a heart condition) start or get worse.

Who should not take Uroxatral?

If you have moderate or severe liver problems, are on antifungal drugs or HIV drugs, are under the age of 18, and if you are already taking an alpha blocker for either blood pressure or prostate problems, you should not take Uroxatral. You should also avoid the drug if you have ever had an allergic reaction to it. Make sure your doctor is aware of any drug reactions you might have experienced.

What should I tell my doctor before I take the first dose of Uroxatral?

Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Uroxatral. Also, talk to your doctor about your complete medical history, especially if you have angina (chest pain), coronary artery disease (such as arteriosclerosis), electrical problems with your heart (QT prolongation), kidney or liver problems, low blood pressure, or prostate cancer.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The recommended dosage is one 10-milligram tablet daily, taken immediately after the same meal each day.

Children: Uroxatral is not indicated for use in children.

How should I take Uroxatral?

Take Uroxatral with food, with the same meal each day.

What should I avoid while taking Uroxatral?

Uroxatral can cause dizziness and even fainting, especially in the first few hours after you take it. Be very careful about driving, operating machinery, or performing dangerous tasks during this period.

What are possible food and drug interactions associated with Uroxatral?

If Uroxatral is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Uroxatral with the following: alpha-blockers (used to treat high blood pressure or BPH), such as carvedilol, prazosin, doxazosin, and tamsulosin; atenolol; cimetidine; diltiazem; itraconazole; ketoconazole; and ritonavir.

What are the possible side effects of Uroxatral?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: dizziness, fatigue, headache, upper respiratory tract infection

Can I receive Uroxatral if I am pregnant or breastfeeding?

Uroxatral is not to be used by women.

What should I do if I miss a dose of Uroxatral?

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and return to your regular schedule. Do not take 2 doses at once.

How should I store Uroxatral?

Store at room temperature and protect from heat, light, and moisture.