Vectibix

Generic name: Panitumumab

What is Vectibix?

Vectibix is used to treat metastatic colorectal cancer while taking or following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy treatments.

What is the most important information I should know about Vectibix?

Vectibix may cause skin problems such as redness, itchiness, dry skin, flaking, cracking, and rash. This drug may also cause reactions from the IV infusion, such as breathing problems, lowered blood pressure, fever, and chills.

Who should not take Vectibix?

You should not take Vectibix if you are allergic to any of its ingredients.

What should I tell my doctor before I take the first dose of Vectibix?

Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Vectibix. Also, talk to your doctor about your complete medical history, especially about all other forms of therapy you have tried before Vectibix.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

The usual dose of Vectibix is 6 milligrams (mg) per 2.2 pounds of body weight administered over 60 minutes as an intravenous (IV) infusion every 14 days. Doses higher than 1,000 mg should be administered over 90 minutes.

How should I take Vectibix?

Vectibix will be given to you through an IV by your doctor, in a hospital setting.

What should I avoid while taking Vectibix?

Avoid receiving rapid IV infusion if you are having a minor reaction to the IV; the infusion should take place over a longer period of time. If you begin to have a severe reaction to the IV, inform your doctor immediately and stop treatment.

You should also avoid the sun whenever possible. When outside, limit sun exposure by wearing sunscreen and a hat.

What are possible food and drug interactions associated with Vectibix?

There are currently no known food or drug interactions associated with Vectibix. However, it is important to notify your physician of all prescription and nonprescription medications you are currently taking.

What are the possible side effects of Vectibix?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: constipation, cough, diarrhea, hair/skin/nail abnormalities, nausea, stomach pain, tiredness/fatigue, vomiting

Can I receive Vectibix if I am pregnant or breastfeeding?

Talk to your doctor if you are pregnant, planning to become pregnant, or are nursing. The effects of Vectibix on pregnancy are unknown, and it may pass into breast milk.

Physicians are encouraged to enroll pregnant patients in Amgen's Pregnancy Surveillance Program by calling 1-800-772-6436.

What should I do if I miss a dose of Vectibix?

Notify your doctor if you miss a dose of Vectibix.

How should I store Vectibix?

Your healthcare provider will store this medication