Viread

Generic name: Tenofovir disproxil fumarate

What is Viread?

Viread is a medication used to treat HIV, the virus that causes AIDS. Viread must be taken in combination with other anti-HIV medications to reduce the amount of virus circulating in your blood, and increase the number of disease fighting cells (CD4 cells) in the blood. Viread is also used to treat hepatitis B.

What is the most important information I should know about Viread?

Viread does not completely eliminate HIV or totally restore the immune system. There is still a danger of serious infections, so you should be sure to see your doctor regularly for monitoring and tests. Notify your doctor immediately of any changes in your general health.

If you have Hepatitis B (HBV) infection or HIV and HBV infection together, you may have a "flare-up" of Hepatitis B, in which the disease suddenly returns in a worse way than before if you stop taking VIREAD. Do not stop taking VIREAD without your doctor's advice.

After stopping VIREAD, tell you doctor immediately about any new, unusual, or worsening symptoms that you notice after stopping treatment. After you stop taking VIREAD, your doctor will still need to check your health and take blood tests to check your liver for several months.

Lactic acidosis (a buildup in the blood of lactic acid, the same substance that causes your muscles to burn during heavy exercise) and severe hepatomegaly (enlargement of the liver) with steatosis, including fatal cases, have been reported. Treatment with VIREAD should be stopped in any patient who shows symptoms that suggest lactic acidosis or pronounced liver toxicity (including nausea, vomiting, unusual or unexpected stomach discomfort, and weakness.

Who should not take Viread?

You should not take Viread if you are allergic or sensitive to it or any of its ingredients. Do not take Viread if you are already taking Truvada or Atripla because Viread contains (tenofovir) one of the same active ingredients in these two medications. Also, do not take Viread if you have not already discontinued treatment with Hepsera (adefovir dipvoxil).

What should I tell my doctor before I take the first dose of Viread?

Tell your doctor about all prescription, over-the-counter, and herbal medication you are taking before beginning treatment with Viread. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems, including hepatitis B, HIV infection, bone problems, or if you are pregnant, breastfeeding, or plan to become pregnant.

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: The usual dosage is 300 milligrams (mg) taken once daily.

Dosages for HIV and hepatitis B patients are the same.

If you have kidney problems, your doctor may recommend that you take Viread less frequently.

How should I take Viread?

Viread should be taken at the same time every day and can be taken with or without food. You should take Viread exactly as your doctor has prescribed and you should not skip doses. Also make sure you are taking other anti-HIV medicines with Viread to prevent resistance.

What should I avoid while taking Viread?

You should not breastfeed while taking Viread.

Avoid running out of your medicine. This could cause the amount of virus in your blood to increase if you stop taking Viread for even a short time.

What are possible food and drug interactions associated with Viread?

If Viread is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Viread with the following: abacavir, atazanavir sulfate, didanosine, emtricitabine, indinavir, lamivudine, lopinavir/ritonavir, and saquinavir/ritonavir.

What are the possible side effects of Viread?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: diarrhea, depression, dizziness, gas, headache, nausea, pain, rash, shortness of breath, vomiting, weakness

Can I receive Viread if I am pregnant or breastfeeding?

Viread. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

What should I do if I miss a dose of Viread?

It is important that you do not miss any doses.

If you miss a dose of Viread, take it as soon as you remember and then take your next scheduled dose at its regular time. If it is almost time for your next dose, do not take the missed dose. Wait and take the next dose at the regular time. Do not double the next dose.

How should I store Viread?

Viread should be kept at room temperature, away from children. Do not store in places that are too hot or too cold. Do not keep medicine that is out of date.