Drugs and Supplements

Prescription Drugs

Zemplar, Paricalcitol, side effects, drug interactions, overdose, dosage

Zemplar

Generic name: Paricalcitol


What is Zemplar?

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Zemplar is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4.


What is the most important information I should know about Zemplar?

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Taking too much vitamin D, as in Zemplar, can cause increased calcium levels, calcium in your urine, and bone disease.


Who should not take Zemplar?

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Do not take Zemplar if you have elevated vitamin D levels, calcium levels, or you are allergic to any of its ingredients.


What should I tell my doctor before I take the first dose of Zemplar?

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Mention all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zemplar. Also, talk to your doctor about your complete medical history.


What is the usual dosage?

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The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medicay history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

Adults: Zemplar capsules may be taken daily or three times a week. When treated three times weekly, the dose should be given no more frequently than every other day.


How should I take Zemplar?

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You should take Zemplar as directed by your doctor. Zemplar may be taken with or without food.


What should I avoid while taking Zemplar?

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Avoid using even nonprescription/over-the-counter drugs without talking to your doctor first.


What are possible food and drug interactions associated with Zemplar?

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If Zemplar is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zemplar with the following: atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole.


What are the possible side effects of Zemplar?

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Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

Side effects may include: allergic reaction, back pain, chest pain, fever, flu, fungal/bacterial infections, headache, pain, stomach pain, viral infection

Symptoms of vitamin D overdose: Early signs and symptoms include bone pain, constipation, dry mouth, headache, nausea/vomiting, metallic taste, muscle pain, sleeplessness, weakness; late signs and symptoms include eye infection, itchiness, light sensitivity, nasal infection, weight loss/loss of appetite


Can I receive Zemplar if I am pregnant or breastfeeding?

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The effects of Zemplar during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.


What should I do if I miss a dose of Zemplar?

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Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule. Do not double the dose.


How should I store Zemplar?

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Store at room temperature.