Rybix ODT

Generic Name: Tramadol

  • What is Rybix ODT?

    Rybix ODT is an opioid (narcotic) painkiller that is used to treat moderate to moderately severe pain.

  • What is the most important information I should know about Rybix ODT?

    Rybix ODT can cause seizures. The risk is greater if you have a history of seizures, are suffering from alcohol or drug withdrawal (abrupt discontinuation or a decrease in the dose of medicines, recreational drugs, or alcohol you take), or nervous system infections. Your risk of seizures may increase if you are taking monoamine oxidase inhibitors (MAOIs), a class of medicines used to treat depression and other psychiatric conditions (such as phenelzine); antidepressant/psychiatric medicines in classes known as selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine and paroxetine), and selective norepinephrine reuptake inhibitors (SNRIs) (such as venlafaxine); certain antidepressants (such as amitriptyline); certain migraine products (such as sumatriptan); or other opioids.

    You can develop a serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) when you are using Rybix ODT, especially if you take it in combination with MAOIs, SSRIs, SNRIs, certain migraine products, or certain antidepressants. Symptoms can include hallucinations, increase in your heart rate, fever, incoordination, and/or stomach problems. Contact your doctor immediately if you develop any of these signs or symptoms.

    Anaphylactoid reactions (a serious and rapid allergic reaction that may result in death if not immediately treated) can occur. Contact your doctor or get emergency help immediately if you experience difficulty breathing; swelling of the throat, tongue, or mouth; or hives.

    Taking Rybix ODT can also lead to abuse, addiction, and dependence.

  • Who should not take Rybix ODT?

    Do not take Rybix ODT if you have attempted suicide or are addiction prone. Do not take Rybix ODT if you are allergic to it or any of it ingredients, or to other opioids.

  • What should I tell my doctor before I take the first dose of Rybix ODT?

    Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Rybix ODT. Also, talk to your doctor about your complete medical history, especially if you have a history of seizures, difficulty breathing, depression, head injury, phenylketonuria (an inability to process phenylalanine, a protein in your body), kidney or liver disease, attempted suicide, or are addicted or allergic to opioids.

  • What is the usual dosage?

    The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.

    Adults ≥17 years: Your doctor will prescribe the appropriate dose for you and will increase your dose as needed, until the desired effect is achieved.

    If you are >75 years old, or have kidney or liver disease, your doctor will adjust your dose appropriately.

  • How should I take Rybix ODT?

    Take Rybix ODT exactly as prescribed by your doctor. Place Rybix ODT tablet on your tongue until it completely disintegrates, and then swallow it with or without water. To open the blister pack, peel back the foil on the blister. Do not push the tablet through the foil. Do not chew, break, or split the tablet.

  • What should I avoid while taking Rybix ODT?

    Do not drive a car or operate dangerous machinery while you are using this medication.

    Do not drink alcohol while you are taking this medication.

    Do not adjust your dose or stop taking Rybix ODT suddenly without first talking to your doctor.

  • What are possible food and drug interactions associated with Rybix ODT?

    If Rybix ODT is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Rybix ODT with the following: alcohol, antidepressants (including MAOIs, SSRIs, SNRIs, or certain antidepressants), antipsychotics (such as haloperidol), carbamazepine, certain migraine products, cyclobenzaprine, digoxin, erythromycin, ketoconazole, linezolid, lithium, phenothiazines (such as promethazine), quinidine, rifampin, sleep aids (such as temazepam), St. John's wort, tranquilizers (such as alprazolam), or warfarin.

  • What are the possible side effects of Rybix ODT?

    Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.

    Side effects may include: constipation, diarrhea, dizziness, drowsiness, dry mouth, headache, itching, nausea, sweating, vomiting, weakness

  • Can I receive Rybix ODT if I am pregnant or breastfeeding?

    The effects of Rybix ODT during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

  • What should I do if I miss a dose of Rybix ODT?

    Rybix ODT should be given under special circumstances determined by your doctor (or given only as needed). If you miss your scheduled dose, contact your doctor or pharmacist for advice.

  • How should I store Rybix ODT?

    Store at room temperature.